Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18408614 | 0.84 | ALDH1A1 (0.50) | ALDH1A1PKMKDM4ETSHRSMN1; SMN2 | |
| SCHEMBL17364196 | 0.80 | SIGMAR1 (0.42) | ALDH1A1PKMSIGMAR1DRD2 | |
| SCHEMBL28633214 | 0.77 | SIGMAR1 (0.41) | ALDH1A1PKMSIGMAR1DRD2 | |
| Hydrochloric Acid SCHEMBL1596638 | 0.76 | DRD4 (0.50) | ALDH1A1PKMTSHRSMN1; SMN2NPC1 | |
| SCHEMBL18412338 | 0.74 | SIGMAR1 (0.47) | SIGMAR1 | |
| SCHEMBL26805924 | 0.71 | DRD4 (0.40) | ALDH1A1PKMKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL18408611 | 0.69 | DRD2 (0.50) | NPC1RAB9AEPHX2MMP2MMP9 | |
| SCHEMBL24489448 | 0.69 | SIGMAR1 (0.48) | ALDH1A1PKMKDM4ESMN1; SMN2SIGMAR1 | |
| SCHEMBL5544399 | 0.68 | QDPR (0.51) | ALDH1A1PKMTSHRSMN1; SMN2NPC1 | |
| SCHEMBL240173 | 0.68 | DRD4 (0.52) | ALDH1A1PKMKDM4ESMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3325443-B1 | PROCESS FOR PREPARING PRIDOPIDINE | Prilenia Neurotherapeutics Ltd (IL) | 2022-06-08 | — | — | EP | disclosed |
| WO-2017015609-A1 | PROCESS FOR PREPARING PRIDOPIDINE | TEVA PHARMACEUTICALS INTERNATIONAL GMBH (CH) | 2017-01-26 | — | — | WO | disclosed |