SCHEMBL1840903

SCHEMBL1840903

Brc1ccccc1-c1nnc(-c2ccccc2)o1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 17/20 0.80
NPC1 O15118 15/20 0.80
SMN1; SMN2 Q16637 12/20 0.80
ALDH1A1 P00352 9/20 0.80
HPGD P15428 7/20 0.80
TP53 P04637 6/20 0.80
TSHR P16473 6/20 0.80
MAPT P10636 4/20 0.80
GAA P10253 2/20 0.71
KDM4E B2RXH2 5/20 0.59
NFKB1 P19838 4/20 0.57
NFKB2 Q00653 4/20 0.57
RELA Q04206 4/20 0.57
ATR Q13535 1/20 0.57
LMNA P02545 1/20 0.57
POLB P06746 2/20 0.56
ATAD2 Q6PL18 1/20 0.55
MAPK1 P28482 2/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
MEN1 O00255 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1838600 0.91 RAB9A (0.72) RAB9ANPC1SMN1; SMN2ALDH1A1HPGD
SCHEMBL28185933 0.90 RAB9A (0.75) RAB9ANPC1SMN1; SMN2ALDH1A1HPGD
SCHEMBL17069888 0.84 RAB9A (0.77) RAB9ANPC1SMN1; SMN2ALDH1A1HPGD
SCHEMBL2271516 0.83 NPC1 (1.00) RAB9ANPC1SMN1; SMN2ALDH1A1HPGD
SCHEMBL2243885 0.82 RAB9A (0.66) RAB9ANPC1SMN1; SMN2ALDH1A1HPGD
SCHEMBL4336383 0.82 RAB9A (0.74) RAB9ANPC1SMN1; SMN2ALDH1A1HPGD
SCHEMBL12765574 0.82 RAB9A (0.76) RAB9ANPC1SMN1; SMN2ALDH1A1HPGD
SCHEMBL46426 0.81 NPC1 (1.00) RAB9ANPC1SMN1; SMN2ALDH1A1HPGD
SCHEMBL16420693 0.80 ATR (0.63) RAB9ANPC1SMN1; SMN2ALDH1A1HPGD
SCHEMBL4343181 0.79 NPC1 (0.94) RAB9ANPC1SMN1; SMN2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10243151-B2 Organic semiconductor material and light-emitting element, light-emitting device, lighting system, and electronic device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-03-26 US disclosed
CN-108947926-A It is a kind of based on pyrene-oxadiazole derivatives bipolarity compound and its application 瑞声科技(南京)有限公司 2018-12-07 CN disclosed
US-9905780-B2 Organic electroluminescent materials containing N-phenylcarboline and organic electroluminescent device by using the same YUAN ZE UNIVERSITY (TW) 2018-02-27 US disclosed
US-9905780-B2 Organic electroluminescent materials containing N-phenylcarboline and organic electroluminescent device by using the same YUAN ZE UNIVERSITY (TW) 2018-02-27 US disclosed
US-9905780-B2 Organic electroluminescent materials containing N-phenylcarboline and organic electroluminescent device by using the same YUAN ZE UNIVERSITY (TW) 2018-02-27 US disclosed
US-20170250352-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-08-31 US disclosed
US-20170162794-A1 ORGANIC ELECTROLUMINESCENT MATERIALS CONTAINING N-PHENYLCARBOLINE AND ORGANIC ELECTROLUMINESCENT DEVICE BY USING THE SAME YUAN ZE UNIVERSITY (TW) 2017-06-08 US disclosed
US-20170162794-A1 ORGANIC ELECTROLUMINESCENT MATERIALS CONTAINING N-PHENYLCARBOLINE AND ORGANIC ELECTROLUMINESCENT DEVICE BY USING THE SAME YUAN ZE UNIVERSITY (TW) 2017-06-08 US disclosed
US-20170162794-A1 ORGANIC ELECTROLUMINESCENT MATERIALS CONTAINING N-PHENYLCARBOLINE AND ORGANIC ELECTROLUMINESCENT DEVICE BY USING THE SAME YUAN ZE UNIVERSITY (TW) 2017-06-08 US disclosed
US-9620723-B2 Organic semiconductor material and light-emitting element, light-emitting device, lighting system, and electronic device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-04-11 US disclosed
US-20150243909-A1 BLUE LUMINESCENT COMPOUNDS E I DU PONT DE NEMOURS AND COMPANY (US) 2015-08-27 US disclosed
US-20150243909-A1 BLUE LUMINESCENT COMPOUNDS E I DU PONT DE NEMOURS AND COMPANY (US) 2015-08-27 US disclosed
US-20150243909-A1 BLUE LUMINESCENT COMPOUNDS E I DU PONT DE NEMOURS AND COMPANY (US) 2015-08-27 US disclosed
CN-104628668-A Synthesis method of pharmaceutical intermediate oxadiazole compound YIN LEI 2015-05-20 CN disclosed
EP-2321862-B1 ORGANIC SEMICONDUCTOR MATERIAL AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, LIGHTING SYSTEM, AND ELECTRONIC DEVICE USING THE SAME SEMICONDUCTOR ENERGY LAB (JP) 2014-11-19 EP disclosed
US-20130112961-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-05-09 US disclosed
US-8343639-B2 Organic semiconductor material and light-emitting element, light-emitting device, lighting system, and electronic device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-01 US disclosed
EP-2321862-A1 ORGANIC SEMICONDUCTOR MATERIAL AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, LIGHTING SYSTEM, AND ELECTRONIC DEVICE USING THE SAME Semiconductor Energy Laboratory Co, Ltd. (JP) 2011-05-18 EP disclosed
WO-2010027004-A1 ORGANIC SEMICONDUCTOR MATERIAL AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, LIGHTING SYSTEM, AND ELECTRONIC DEVICE USING THE SAME SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-03-11 WO disclosed
US-20100060155-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10243151-B2 Organic semiconductor material and light-emitting element, light-emitting device, lighting system, and electronic device using the same OXA1L, BECN1, MAP1LC3A RAB9A 3158/4885NPC1 4299/4885SMN1; SMN2 3015/4885
US-20170250352-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same OXA1L, BECN1, MAP1LC3A RAB9A 3158/4885NPC1 4299/4885SMN1; SMN2 3015/4885
US-20100060155-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same OXA1L, BECN1, MAP1LC3A RAB9A 3158/4885NPC1 4299/4885SMN1; SMN2 3015/4885
US-20130112961-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same OXA1L, BECN1, MAP1LC3A RAB9A 3158/4885NPC1 4299/4885SMN1; SMN2 3015/4885
US-20170162794-A1 ORGANIC ELECTROLUMINESCENT MATERIALS CONTAINING N-PHENYLCARBOLINE AND ORGANIC ELECTROLUMINESCENT DEVICE BY USING THE SAME EML4, CCNL2, EPB41L2 RAB9A 3116/4885NPC1 1823/4885SMN1; SMN2 2320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.