Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 2/20 | 0.31 |
| ▸ | CCRL2 | O00421 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18409283 | 0.88 | JAK2 (0.34) | LMNAALDH1A1TSHRNPSR1PPARG | |
| SCHEMBL18409113 | 0.86 | ALDH1A1 (0.36) | ALDH1A1NPSR1PPARGMAPTKMT2A | |
| SCHEMBL18409110 | 0.83 | POLB (0.33) | LMNAALDH1A1TSHRPPARGJAK2 | |
| SCHEMBL18409291 | 0.81 | JAK2 (0.37) | ALDH1A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL18409360 | 0.80 | MEN1 (0.36) | LMNAALDH1A1NPSR1MAPTKMT2A | |
| SCHEMBL18409164 | 0.80 | JAK2 (0.42) | LMNAALDH1A1TSHRJAK2JAK1 | |
| SCHEMBL18409541 | 0.79 | PIK3CA (0.35) | LMNAALDH1A1TSHRMAPTJAK2 | |
| SCHEMBL18409180 | 0.79 | TYK2 (0.35) | LMNAALDH1A1TSHRNPSR1MAPT | |
| SCHEMBL18409277 | 0.79 | JAK2 (0.37) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL18409116 | 0.78 | JAK2 (0.38) | ALDH1A1JAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017012647-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS | GALAPAGOS NV (BE) | 2017-01-26 | — | — | WO | disclosed |