Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13998896 | 0.81 | NPSR1 (0.46) | NPSR1L3MBTL1KDM4EALDH1A1KMT2A | |
| SCHEMBL1841307 | 0.79 | KDM4E (0.37) | KDM4EKMT2A | |
| SCHEMBL27584076 | 0.79 | KDM4E (0.47) | NPSR1L3MBTL1KDM4EALDH1A1KMT2A | |
| SCHEMBL8201600 | 0.78 | NPSR1 (0.43) | NPSR1L3MBTL1KDM4EALDH1A1KMT2A | |
| SCHEMBL25037121 | 0.78 | NPSR1 (0.43) | NPSR1L3MBTL1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL17603768 | 0.77 | NPSR1 (0.44) | NPSR1L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL1841306 | 0.77 | KDM4E (0.46) | NPSR1L3MBTL1KDM4EALDH1A1KMT2A | |
| SCHEMBL16712807 | 0.74 | ALDH1A1 (0.44) | KDM4EALDH1A1KMT2AHPGDHSD17B10 | |
| SCHEMBL3321442 | 0.74 | CA12 (0.45) | NPSR1KDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL21072556 | 0.73 | NOS3 (0.47) | NPSR1L3MBTL1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373210-B1 | HETEROCYCLIC DIAMIDE INVERTEBRATE PEST CONTROL AGENTS | DU PONT (US) | 2011-05-18 | — | — | EP | disclosed |
| US-7560564-B2 | Heterocyclic diamide invertebrate pest control agents | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-14 | — | — | US | disclosed |
| CN-100352808-C | Heterocyclic diamide invertebrate pest control agents | DU PONT (US) | 2007-12-05 | — | — | CN | disclosed |
| US-20060205748-A1 | Heterocyclic diamide invertebrate pest control agents | ANNIS GARY D | 2006-09-14 | — | — | US | disclosed |
| US-20040102324-A1 | Heterocyclic diamide invertebrate pest control agents | E.I. DU PONT DE NEMOURS AND COMPANY | 2004-05-27 | — | — | US | disclosed |
| CN-1494530-A | Heterocyclic diamide invertebrate pest control agents | �Ű˾ | 2004-05-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205748-A1 | Heterocyclic diamide invertebrate pest control agents | DDT, DBF4, C1S | NPSR1 158/4885L3MBTL1 279/4885KDM4E 1378/4885 |
| US-20040102324-A1 | Heterocyclic diamide invertebrate pest control agents | DDT, DBF4, DDC | NPSR1 495/4885L3MBTL1 487/4885KDM4E 835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.