Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18409660 | 0.91 | DRD2 (0.48) | CHRM4DRD2DRD4GRM2CNR2 | |
| SCHEMBL18409662 | 0.82 | DRD2 (0.47) | DRD2DRD4SMN1; SMN2KDM4EMAPK14 | |
| SCHEMBL18409293 | 0.81 | CASP1 (0.43) | DRD2DRD4KDM4EMAPK14ALDH1A1 | |
| SCHEMBL18409622 | 0.77 | DRD2 (0.51) | DRD2DRD4SMN1; SMN2KDM4EMAPK14 | |
| SCHEMBL9667283 | 0.76 | CHRM4 (0.69) | CHRM4DRD2DRD4GRM2TRPV6 | |
| SCHEMBL18409305 | 0.73 | DRD4 (0.51) | DRD2DRD4SMN1; SMN2MAPK14LMNA | |
| SCHEMBL18409491 | 0.72 | OPRL1 (0.57) | CHRM4DRD2DRD4TRPV6SMN1; SMN2 | |
| SCHEMBL18409471 | 0.72 | MAPK13 (0.49) | KDM4EMAPK14LMNAPOLBSIGMAR1 | |
| SCHEMBL18409352 | 0.72 | DRD4 (0.46) | DRD2DRD4SMN1; SMN2KDM4ELMNA | |
| SCHEMBL18409624 | 0.71 | ALDH1A1 (0.49) | DRD2DRD4KDM4ELMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017011920-A1 | COMPOUNDS AND USES THEREOF IN THE TREATMENT OF CANCERS AND OTHER MEDICAL CONDITIONS | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2017-01-26 | — | — | WO | disclosed |