Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30006360 | 0.90 | ALDH1A1 (0.45) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL23530227 | 0.90 | ALDH1A1 (0.45) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL18406187 | 0.83 | HRH3 (0.44) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL24493477 | 0.82 | TSHR (0.46) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL30620837 | 0.82 | ALOX5AP (0.46) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL18409807 | 0.82 | RIPK1 (0.48) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL13388309 | 0.81 | TSHR (0.43) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL30476145 | 0.79 | ALOX5AP (0.43) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL30541398 | 0.79 | TSHR (0.43) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL1791760 | 0.78 | RIPK1 (0.51) | ALDH1A1TSHRLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170022185-A1 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY | 2017-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022185-A1 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | PPOX, DDO, DDC | ALDH1A1 149/4885TSHR 3708/4885LMNA 4743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.