⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17187889 | 0.81 | HTR2A (0.31) | — | |
| SCHEMBL17187881 | 0.75 | MTNR1A (0.36) | — | |
| SCHEMBL18428159 | 0.74 | MTNR1A (0.36) | — | |
| SCHEMBL17187806 | 0.72 | CYP1A2 (0.37) | — | |
| SCHEMBL30260100 | 0.71 | KDM4E (0.33) | — | |
| SCHEMBL31670075 | 0.70 | CYP2A6 (0.52) | — | |
| SCHEMBL5644819 | 0.70 | ALDH1A1 (0.40) | — | |
| SCHEMBL17187860 | 0.70 | CYP1A2 (0.44) | — | |
| SCHEMBL6417161 | 0.65 | HTR2A (0.35) | — | |
| SCHEMBL6584082 | 0.65 | MTNR1A (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3134392-B1 | SULFONAMIDE DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2019-01-02 | — | — | EP | disclosed |
| US-9840482-B2 | Sulfonamide derivatives and pharmaceutical applications thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-12-12 | — | — | US | disclosed |
| US-20170037017-A1 | Sulfonamide Derivatives And Pharmaceutical Applications Thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-02-09 | — | — | US | disclosed |