Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035199 | 0.78 | CYP1A2 (0.52) | ALDH1A1MAPTCYP2D6MEN1KMT2A | |
| SCHEMBL30260041 | 0.76 | MEN1 (0.30) | ALDH1A1MEN1KMT2A | |
| SCHEMBL23043332 | 0.76 | MEN1 (0.30) | ALDH1A1MEN1KMT2A | |
| SCHEMBL31670075 | 0.76 | CYP2A6 (0.52) | KDM4E | |
| SCHEMBL17187881 | 0.72 | MTNR1A (0.36) | KDM4EALDH1A1HPGDHTT | |
| SCHEMBL17187889 | 0.72 | HTR2A (0.31) | CYP2D6 | |
| SCHEMBL18428147 | 0.71 | — | — | |
| SCHEMBL25410815 | 0.70 | NQO2 (0.38) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL23043175 | 0.70 | IRAK4 (0.32) | — | |
| SCHEMBL6417161 | 0.70 | HTR2A (0.35) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023056951-A1 | ARYL-SUBSTITUTED HETEROCYCLIC COMPOUND | 杭州德睿智药科技有限公司 | 2023-04-13 | — | — | WO | disclosed |