Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | PTPN2 | P17706 | 2/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 2/20 | 1.00 |
| ▸ | PTPN6 | P29350 | 2/20 | 1.00 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 1.00 |
| ▸ | USP7 | Q93009 | 2/20 | 1.00 |
| ▸ | PYGM | P11217 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.80 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.80 |
| ▸ | GABRP | O00591 | 1/20 | 0.80 |
| ▸ | GABRD | O14764 | 1/20 | 0.80 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.80 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.80 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.80 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.80 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.80 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.80 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Corosolic Acid SCHEMBL13735311 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL4456542 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL1157257 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL13629647 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL12181488 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Pygenic Acid A SCHEMBL4962201 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL14628105 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL13629630 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL22027588 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL4456541 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250002490-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | SHENZHEN HIGHTIDE BIOPHARMACEUTICAL LTD (CN) | 2025-01-02 | — | — | US | disclosed |
| WO-2024004951-A1 | BEVERAGE, AND METHOD FOR REDUCING INHERENT SOURNESS ORIGINATING FROM CITRIC ACID AND/OR SALT THEREOF IN BEVERAGE | サントリーホールディングス株式会社 | 2024-01-04 | — | — | WO | disclosed |
| WO-2022202459-A1 | COROSOLIC-ACID-CONTAINING BEVERAGE AND METHOD FOR MANUFACTURING SAME | サントリーホールディングス株式会社 | 2022-09-29 | — | — | WO | disclosed |
| US-10988471-B2 | Pharmaceutical composition comprising berberine ursodeoxycholic acid salt for the treatment of various diseases or disorders | SHENZHEN HIGHTIDE BIOPHARMACEUTICAL, LTD. (CN) | 2021-04-27 | — | — | US | disclosed |
| US-20190211007-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | SHENZHEN HIGHTIDE BIOPHARMACEUTICAL, LTD. (CN) | 2019-07-11 | — | — | US | disclosed |
| US-10301303-B2 | Berberine salts, ursodeoxycholic salts and combinations, methods of preparation and application thereof | SHENZHEN HIGHTIDE BIOPHARMACEUTICAL, LTD. (CN) | 2019-05-28 | — | — | US | disclosed |
| US-20180050048-A1 | CONJUGATE COMPOUNDS OF URSODEOXYCHOLIC, BERBERINE OR L-CARNITINE, AND COMPOSITIONS AND METHODS THEREOF | SHENZHEN HIGHTIDE BIOPHARMACEUTICAL, LTD. (CN) | 2018-02-22 | — | — | US | disclosed |
| US-20170037043-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | SHENZHEN HIGHTIDE BIOPHARMACEUTICAL, LTD. (CN) | 2017-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170037043-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | CYP27A1, NR1H4, CYP7A1 | HSD11B1 101/4885POLB 2698/4885PTPN2 4122/4885 |
| US-20250002490-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | CYP27A1, NR1H4, CYP7A1 | HSD11B1 101/4885POLB 2698/4885PTPN2 4122/4885 |
| US-20190211007-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | CYP27A1, NR1H4, CYP7A1 | HSD11B1 101/4885POLB 2698/4885PTPN2 4122/4885 |
| US-10988471-B2 | Pharmaceutical composition comprising berberine ursodeoxycholic acid salt for the treatment of various diseases or disorders | CYP27A1, SLC10A1, NR1H4 | HSD11B1 93/4885POLB 2990/4885PTPN2 3226/4885 |
| US-20180050048-A1 | CONJUGATE COMPOUNDS OF URSODEOXYCHOLIC, BERBERINE OR L-CARNITINE, AND COMPOSITIONS AND METHODS THEREOF | HMGCR, COASY, CPT1A | HSD11B1 654/4885POLB 2462/4885PTPN2 4853/4885 |
| US-10301303-B2 | Berberine salts, ursodeoxycholic salts and combinations, methods of preparation and application thereof | CYP27A1, NR1H4, CYP7A1 | HSD11B1 101/4885POLB 2698/4885PTPN2 4122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.