Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | PTPN2 | P17706 | 2/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 2/20 | 1.00 |
| ▸ | PTPN6 | P29350 | 2/20 | 1.00 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 1.00 |
| ▸ | USP7 | Q93009 | 2/20 | 1.00 |
| ▸ | PYGM | P11217 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.80 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.80 |
| ▸ | GABRP | O00591 | 1/20 | 0.80 |
| ▸ | GABRD | O14764 | 1/20 | 0.80 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.80 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.80 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.80 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.80 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.80 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.80 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Corosolic Acid SCHEMBL13735311 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL4456542 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL18428539 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL1157257 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL13629647 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL12181488 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL14628105 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL13629630 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL22027588 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL4456541 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116660543-A | Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof | 中国人民解放军陆军军医大学第一附属医院 | 2023-08-29 | — | — | CN | claimed |
| CN-113975283-B | Anti-angiogenic composition containing sepsis a isolated from Prunella vulgaris as active ingredient | 韩国韩医药振兴院 | 2024-12-10 | — | — | CN | disclosed |
| US-20200163983-A1 | SAPONIN COMPOUND TARGETING PD-1 AND APPLICATION THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2020-05-28 | — | — | US | disclosed |
| US-20180118657-A1 | METHODS FOR INHIBITING MUSCLE ATROPHY | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2018-05-03 | — | — | US | disclosed |
| US-20130203712-A1 | METHODS FOR INHIBITING MUSCLE ATROPHY | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2013-08-08 | — | — | US | disclosed |
| EP-0914139-B1 | ANTIVIRAL AGENTS FROM PLANT EXTRACTS AND USE FOR TREATMENT OF VIRAL INFECTIONS | TSAI HSIU-HSIEN (TW) | 2008-02-27 | — | — | EP | disclosed |
| US-20060235078-A1 | Insulin secretion potentiator | USE-TECHNO CORPORATION | 2006-10-19 | — | — | US | disclosed |
| EP-1674089-A1 | ACCELERATOR FOR INITIAL INSULIN SECRETION | Use-Techno Corporation (JP) | 2006-06-28 | — | — | EP | disclosed |
| WO-2006054370-A1 | GLUCONEOGENESIS INHIBITING AGENT | USE-TECHNO CORPORATION (JP) | 2006-05-26 | — | — | WO | disclosed |
| US-20050143464-A1 | With low side effects, which rapidly stimulate early insulin secretion and suppress blood glucose increase only at mealtimes; antidiabetic agent; triterpene acids or alcohols with picene ring; corosolic acids; oleanene acids; ursenoic acids; banaba plant extracts | USE-TECHNO CORPORATION | 2005-06-30 | — | — | US | disclosed |
| US-6214350-B1 | Process for preparing an anti-viral medicinal product from plant extracts | HWANG SHIE-MING (US) | 2001-04-10 | — | — | US | disclosed |
| EP-0914139-A2 | ANTIVIRAL AGENTS FROM PLANT EXTRACTS AND USE FOR TREATMENT OF VIRAL INFECTIONS | Sage, R & D (US) | 1999-05-12 | — | — | EP | disclosed |
| WO-1998001144-A9 | ANTIVIRAL AGENTS FROM PLANT EXTRACTS AND USE FOR TREATMENT OF VIRAL INFECTIONS | — | 1999-03-18 | — | — | WO | disclosed |
| US-5837257-A | COMPOSITIONS DERIVED FROM CHINESE HERBAL MEDICINES, MEDICINAL PLANTS, AND EXTRACTS THEREOF | SAGE R&D (US) | 1998-11-17 | — | — | US | disclosed |
| WO-1998001144-A1 | ANTIVIRAL AGENTS FROM PLANT EXTRACTS AND USE FOR TREATMENT OF VIRAL INFECTIONS | SAGE R & D (US) | 1998-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143464-A1 | With low side effects, which rapidly stimulate early insulin secretion and suppress blood glucose increase only at mealtimes; antidiabetic agent; triterpene acids or alcohols with picene ring; corosolic acids; oleanene acids; ursenoic acids; banaba plant extracts | GPR119, IRS1, AMY1A | HSD11B1 18/4885POLB 2537/4885PTPN2 2179/4885 |
| US-20200163983-A1 | SAPONIN COMPOUND TARGETING PD-1 AND APPLICATION THEREOF | PDCD1, CD274, PDCD1LG2 | HSD11B1 110/4885POLB 3215/4885PTPN2 235/4885 |
| US-20060235078-A1 | Insulin secretion potentiator | IAPP, GPR119, IRS1 | HSD11B1 36/4885POLB 4362/4885PTPN2 1100/4885 |
| US-20180118657-A1 | METHODS FOR INHIBITING MUSCLE ATROPHY | TNNC1, PYGM, GYS1 | HSD11B1 130/4885POLB 3218/4885PTPN2 4663/4885 |
| US-20130203712-A1 | METHODS FOR INHIBITING MUSCLE ATROPHY | TNNC1, PYGM, GYS1 | HSD11B1 130/4885POLB 3218/4885PTPN2 4663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.