Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | PTPN2 | P17706 | 2/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 2/20 | 1.00 |
| ▸ | PTPN6 | P29350 | 2/20 | 1.00 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 1.00 |
| ▸ | USP7 | Q93009 | 2/20 | 1.00 |
| ▸ | PYGM | P11217 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.80 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.80 |
| ▸ | GABRP | O00591 | 1/20 | 0.80 |
| ▸ | GABRD | O14764 | 1/20 | 0.80 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.80 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.80 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.80 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.80 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.80 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.80 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Corosolic Acid SCHEMBL13735311 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL4456542 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL18428539 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL13629647 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL12181488 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Pygenic Acid A SCHEMBL4962201 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL14628105 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL13629630 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL22027588 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL4456541 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115074399-B | Loquat triterpenic acid synthesis key enzyme gene EjCYP A1/2 and EjCYP716C1/2 and application | 华南农业大学 | 2025-04-04 | — | — | CN | disclosed |
| US-20250108036-A1 | COMPOSITIONS FOR REMOVING SENESCENT CELLS AND USES THEREOF | LIFECEUTIX CO., LTD. (KR) | 2025-04-03 | — | — | US | disclosed |
| CN-118923595-A | Method for preventing and treating taura syndrome of litopenaeus vannamei | 信邦海洋生物科技有限公司 | 2024-11-12 | — | — | CN | disclosed |
| EP-4431102-A1 | COMPOSITIONS FOR REMOVING SENESCENT CELLS AND USES THEREOF | Lifeceutix Co., Ltd. (KR) | 2024-09-18 | — | — | EP | disclosed |
| CN-115074374-B | Apple triterpenic acid synthesis key enzyme genes MdTYP 716A2 and MdTYP 716C1 and application thereof | 福建省农业科学院果树研究所 | 2023-08-08 | — | — | CN | disclosed |
| CN-115721653-A | Application of corosolic acid in preparation of medicine for treating acute lung injury caused by sepsis | 武汉大学 | 2023-03-03 | — | — | CN | disclosed |
| CN-115074374-A | Apple triterpenic acid synthesis key enzyme genes MdCYP716A2 and MdCYP716C1 and application thereof | 福建省农业科学院果树研究所 | 2022-09-20 | — | — | CN | disclosed |
| CN-115074399-A | Loquat triterpenic acid synthesis key enzyme genes EjCYP716A1/2 and EjCYP716C1/2 and application thereof | 华南农业大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-113476438-B | Hypoglycemic composition containing dihydro morin and application thereof | 中国农业科学院郑州果树研究所 | 2022-09-09 | — | — | CN | disclosed |
| CN-110938640-B | Alpha-amyrin synthetase gene EjAAS1 and application thereof | 华南农业大学 | 2022-04-08 | — | — | CN | disclosed |
| CN-106581219-A | Medicine composition for treating childhood amygdalitis | 济南昊雨青田医药技术有限公司 | 2017-04-26 | — | — | CN | disclosed |
| CN-106581100-A | Pharmaceutical composition for laryngitis treatment and preparation method thereof | 济南昊雨青田医药技术有限公司 | 2017-04-26 | — | — | CN | disclosed |
| CN-103725743-A | Biological catalytic synthesis method of corosolic acid | UNIV ZUNYI MEDICAL | 2014-04-16 | — | — | CN | disclosed |
| US-7893263-B2 | Structural analogs of corosolic acid having anti-diabetic and anti-inflammatory properties | LAILA NUTRACEUTICALS (IN) | 2011-02-22 | — | — | US | disclosed |
| US-7780997-B2 | Pharmaceutically active extracts of vitex leucoxylon, a process of extracting the same and a method of treating diabetes and inflammatory diseases therewith | LAILA IMPEX (IN) | 2010-08-24 | — | — | US | disclosed |
| US-20080199543-A1 | Pharmaceutically Active Extracts of Vitex Leucoxylon, a Process of Extracting the Same and a Method of Treating Diabetes and Inflammatory Diseases Therewith | LAILA IMPEX (IN) | 2008-08-21 | — | — | US | disclosed |
| US-20070167521-A1 | Novel structural analogs of corosolic acid having anti-diabetic and anti-inflammatory properties | LAILA NUTRACEUTICALS (IN) | 2007-07-19 | — | — | US | disclosed |
| EP-1773749-A1 | NOVEL STRUCTURAL ANALOGS OF COROSOLIC ACID HAVING ANTI-DIABETIC AND ANTI-INFLAMMATORY PROPERTIES | Gokaraju, Ganga, Raju (IN) | 2007-04-18 | — | — | EP | disclosed |
| WO-2007029263-A1 | PHARMACEUTICALLY ACTIVE EXTRACTS OF VITEX LEUCOXYLON, A PROCESS OF EXTRACTING THE SAME AND A METHOD OF TREATING DIABETES AND INFLAMMATORY DISEASES THEREWITH | GOKARAJU GANGA RAJU (IN) | 2007-03-15 | — | — | WO | disclosed |
| WO-2006006178-A1 | NOVEL STRUCTURAL ANALOGS OF COROSOLIC ACID HAVING ANTI-DIABETIC AND ANTI-INFLAMMATORY PROPERTIES | GOKARAJU GANGA RAJU (IN) | 2006-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167521-A1 | Novel structural analogs of corosolic acid having anti-diabetic and anti-inflammatory properties | HCAR3, HCAR1, HCAR2 | HSD11B1 406/4885POLB 4416/4885PTPN2 2202/4885 |
| US-20250108036-A1 | COMPOSITIONS FOR REMOVING SENESCENT CELLS AND USES THEREOF | GLA, LIMS1, TP53 | HSD11B1 3441/4885POLB 1646/4885PTPN2 590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.