Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2716313 | 0.81 | TSHR (0.61) | ALDH1A1HTTPOLBLMNATSHR | |
| SCHEMBL19219785 | 0.81 | ALDH1A1 (0.40) | ALDH1A1HTTPOLBLMNATSHR | |
| SCHEMBL18433965 | 0.76 | CYP1A2 (0.30) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18433800 | 0.76 | LMNA (0.32) | LMNA | |
| SCHEMBL18738729 | 0.76 | HSP90AB1 (0.37) | — | |
| SCHEMBL3014825 | 0.74 | SLC11A2 (0.46) | ALDH1A1HTTLMNACYP1A2CYP2D6 | |
| SCHEMBL18433811 | 0.73 | TSHR (0.40) | ALDH1A1LMNATSHRCYP1A2CYP2D6 | |
| SCHEMBL10139141 | 0.71 | ALDH1A1 (0.57) | ALDH1A1LMNATSHRMAPTMEN1 | |
| SCHEMBL1145638 | 0.71 | CYP1A2 (0.58) | POLBLMNACYP1A2MAOB | |
| SCHEMBL10139180 | 0.71 | ALDH1A1 (0.40) | ALDH1A1LMNATSHRCYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3207037-B1 | FLUORINATED BENZOFURANYL-PYRIMIDINE DERIVATIVES CONTAINING A SULFONE GROUP | Bayer Pharma AG (DE) | 2019-01-23 | — | — | EP | disclosed |
| EP-2920153-B1 | 4-(ORTHO)-FLUOROPHENYL-5-FLUOROPYRIMIDIN-2-YL AMINES CONTAINING A SULFOXIMINE GROUP | Bayer Pharma AG (DE) | 2017-02-01 | — | — | EP | disclosed |