Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13723487 | 0.83 | TSHR (0.38) | LMNA | |
| SCHEMBL19220255 | 0.83 | LMNA (0.35) | LMNA | |
| SCHEMBL18433965 | 0.79 | CYP1A2 (0.30) | — | |
| SCHEMBL18738729 | 0.79 | HSP90AB1 (0.37) | — | |
| SCHEMBL3297051 | 0.77 | IDO1 (0.41) | LMNA | |
| SCHEMBL18433792 | 0.76 | ALDH1A1 (0.39) | LMNA | |
| SCHEMBL18738841 | 0.71 | CNR1 (0.31) | — | |
| SCHEMBL18738859 | 0.70 | CNR1 (0.32) | — | |
| SCHEMBL18387130 | 0.70 | LMNA (0.37) | LMNA | |
| SCHEMBL18731843 | 0.69 | LMNA (0.35) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3126338-B1 | DISUBSTITUTED 5-FLUORO PYRIMIDINE DERIVATIVES CONTAINING A SULFONDIIMINE GROUP | Bayer Pharma AG (DE) | 2019-09-04 | — | — | EP | disclosed |
| EP-3207037-B1 | FLUORINATED BENZOFURANYL-PYRIMIDINE DERIVATIVES CONTAINING A SULFONE GROUP | Bayer Pharma AG (DE) | 2019-01-23 | — | — | EP | disclosed |
| EP-2920153-B1 | 4-(ORTHO)-FLUOROPHENYL-5-FLUOROPYRIMIDIN-2-YL AMINES CONTAINING A SULFOXIMINE GROUP | Bayer Pharma AG (DE) | 2017-02-01 | — | — | EP | disclosed |