Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.34 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2716313 | 0.82 | TSHR (0.61) | ALDH1A1HTTPOLBLMNATSHR | |
| SCHEMBL18433792 | 0.81 | ALDH1A1 (0.39) | ALDH1A1HTTPOLBLMNATSHR | |
| SCHEMBL17347330 | 0.77 | TSHR (0.44) | ALDH1A1LMNATSHRCYP1A2CYP2D6 | |
| SCHEMBL3014825 | 0.76 | SLC11A2 (0.46) | ALDH1A1HTTLMNACYP1A2CYP2D6 | |
| SCHEMBL19220255 | 0.74 | LMNA (0.35) | LMNAEPHX1 | |
| SCHEMBL14793409 | 0.74 | EPHX1 (0.31) | CYP1A2CYP2C9CYP2C19EPHX1 | |
| SCHEMBL19220492 | 0.74 | TSHR (0.39) | ALDH1A1LMNATSHRCYP1A2CYP2D6 | |
| SCHEMBL17347353 | 0.73 | TSHR (0.55) | ALDH1A1HTTPOLBLMNATSHR | |
| SCHEMBL14134783 | 0.73 | AKR1B1 (0.52) | ALDH1A1HTTPOLBLMNATSHR | |
| SCHEMBL14551073 | 0.71 | TSHR (0.43) | ALDH1A1HTTPOLBLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902716-B2 | Fluorinated benzofuranyl-pyrimidine derivatives containing a sulfone group | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-02-27 | — | — | US | disclosed |
| US-20170226092-A1 | FLUORINATED BENZOFURANYL-PYRIMIDINE DERIVATIVES CONTAINING A SUFLONE GROUP | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170226092-A1 | FLUORINATED BENZOFURANYL-PYRIMIDINE DERIVATIVES CONTAINING A SUFLONE GROUP | FANCF, FLI1, FANCD2 | ALDH1A1 189/4885HTT 4344/4885POLB 552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.