Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 7/20 | 0.65 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PIK3R2 | O00459 | 8/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434689 | 0.90 | SLC40A1 (0.52) | SLC40A1METAP2RAB9AKDM4ELMNA | |
| SCHEMBL18434841 | 0.88 | SLC40A1 (0.52) | SLC40A1METAP2RAB9AKDM4ELMNA | |
| SCHEMBL18434473 | 0.82 | SLC40A1 (0.68) | SLC40A1METAP2KDM4ELMNAMAPT | |
| SCHEMBL18434703 | 0.80 | SLC40A1 (0.69) | SLC40A1METAP2RAB9AKDM4EHSP90AA1 | |
| SCHEMBL11973440 | 0.78 | SLC40A1 (1.00) | SLC40A1 | |
| SCHEMBL18434845 | 0.77 | SLC40A1 (0.58) | SLC40A1METAP2KDM4ELMNAHSP90AA1 | |
| SCHEMBL18434504 | 0.77 | SLC40A1 (0.62) | SLC40A1MAPTPIK3R2PIK3CDPIK3CA | |
| SCHEMBL18434412 | 0.77 | SLC40A1 (0.55) | SLC40A1METAP2KDM4ELMNAHSP90AA1 | |
| SCHEMBL18434496 | 0.75 | SLC40A1 (0.61) | SLC40A1KDM4ELMNAHSP90AA1MAPT | |
| SCHEMBL18434673 | 0.75 | SLC40A1 (0.44) | SLC40A1METAP2KDM4ELMNAHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |