Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 8/20 | 0.62 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | NCF1 | P14598 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.38 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434849 | 0.90 | SLC40A1 (0.60) | SLC40A1METAP1NCF1MAPTTSHR | |
| SCHEMBL18434448 | 0.89 | SLC40A1 (0.61) | SLC40A1METAP1NCF1PRKDCMAPT | |
| SCHEMBL18434803 | 0.81 | SLC40A1 (0.66) | SLC40A1TSHR | |
| SCHEMBL18434485 | 0.80 | SLC40A1 (0.67) | SLC40A1 | |
| SCHEMBL18434714 | 0.79 | SLC40A1 (0.66) | SLC40A1MAPTTSHRMAPK1 | |
| SCHEMBL18434857 | 0.78 | SLC40A1 (0.49) | SLC40A1MAPTTSHR | |
| SCHEMBL18434497 | 0.77 | SLC40A1 (0.65) | SLC40A1PIK3CAPIK3CDPIK3CGPIK3R2 | |
| SCHEMBL11972906 | 0.77 | SLC40A1 (1.00) | SLC40A1 | |
| SCHEMBL18434505 | 0.77 | SLC40A1 (0.60) | SLC40A1METAP1PIK3CANCF1PIK3CD | |
| SCHEMBL12475058 | 0.75 | SLC40A1 (0.55) | SLC40A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |