Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 14/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434466 | 0.83 | SLC40A1 (0.69) | SLC40A1SMN1; SMN2KDM4E | |
| SCHEMBL18434703 | 0.80 | SLC40A1 (0.69) | SLC40A1SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL11973821 | 0.79 | SLC40A1 (1.00) | SLC40A1 | |
| SCHEMBL18434826 | 0.79 | SLC40A1 (0.63) | SLC40A1SMN1; SMN2KDM4EALDH1A1CDC7 | |
| SCHEMBL18434667 | 0.78 | SLC40A1 (0.65) | SLC40A1SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL18434683 | 0.78 | SLC40A1 (0.62) | SLC40A1SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL18434845 | 0.76 | SLC40A1 (0.58) | SLC40A1SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL18434673 | 0.75 | SLC40A1 (0.44) | SLC40A1SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL18434496 | 0.75 | SLC40A1 (0.61) | SLC40A1SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL18434412 | 0.75 | SLC40A1 (0.55) | SLC40A1SMN1; SMN2KDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |