Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 16/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434472 | 0.81 | KDM4E (0.39) | SLC40A1HIF1AALDH1A1MAPTKDM4E | |
| SCHEMBL18434412 | 0.79 | SLC40A1 (0.55) | SLC40A1HIF1ACCR1CCR8ALDH1A1 | |
| SCHEMBL18434664 | 0.79 | SLC40A1 (0.55) | SLC40A1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL12475058 | 0.79 | SLC40A1 (0.55) | SLC40A1CYP2C19ALDH1A1MAPTKDM4E | |
| SCHEMBL11973826 | 0.77 | KDM4E (0.46) | SLC40A1KDM4EL3MBTL1 | |
| SCHEMBL11973692 | 0.76 | SLC40A1 (0.48) | SLC40A1 | |
| SCHEMBL18434406 | 0.76 | SLC40A1 (0.58) | SLC40A1KDM4EMEN1KMT2A | |
| SCHEMBL11973242 | 0.74 | SLC40A1 (1.00) | SLC40A1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL18434849 | 0.73 | SLC40A1 (0.60) | SLC40A1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL18434855 | 0.73 | SLC40A1 (0.62) | SLC40A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |