Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 8/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NFKBIA | P25963 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | RELA | Q04206 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434660 | 0.76 | SLC40A1 (0.53) | SLC40A1KDM4EMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL18434408 | 0.72 | SLC40A1 (0.57) | SLC40A1NPC1KDM4EMAPTL3MBTL1 | |
| SCHEMBL11973562 | 0.71 | SLC40A1 (1.00) | SLC40A1KDM4EMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL18434454 | 0.71 | SLC40A1 (0.53) | SLC40A1KDM4EMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL18434688 | 0.68 | SLC40A1 (0.53) | SLC40A1NPC1KDM4EMAPTL3MBTL1 | |
| SCHEMBL18434668 | 0.65 | SLC40A1 (0.56) | SLC40A1KDM4EMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL18434687 | 0.65 | SLC40A1 (0.48) | SLC40A1KDM4EMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL16285217 | 0.64 | SLC40A1 (0.58) | SLC40A1KDM4EMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL18434678 | 0.64 | SLC40A1 (0.57) | SLC40A1KDM4EMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL14224305 | 0.62 | ALDH1A1 (0.62) | SLC40A1NPC1KDM4EMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |