Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 5/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CASP9 | P55211 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434712 | 0.82 | SLC40A1 (0.64) | SLC40A1L3MBTL1KDM4ENPC1RAB9A | |
| SCHEMBL18434703 | 0.81 | SLC40A1 (0.69) | SLC40A1L3MBTL1KDM4ENPC1RAB9A | |
| SCHEMBL11973723 | 0.80 | SLC40A1 (1.00) | SLC40A1 | |
| SCHEMBL18434471 | 0.77 | SLC40A1 (0.66) | SLC40A1L3MBTL1KDM4EMETAP2ALDH1A1 | |
| SCHEMBL18434682 | 0.73 | SLC40A1 (0.50) | SLC40A1L3MBTL1KDM4ERAB9AHSP90AA1 | |
| SCHEMBL18434678 | 0.73 | SLC40A1 (0.57) | SLC40A1L3MBTL1KDM4EHSP90AA1METAP2 | |
| SCHEMBL18434821 | 0.70 | SLC40A1 (0.64) | SLC40A1L3MBTL1KDM4ERAB9AHSP90AA1 | |
| SCHEMBL18434817 | 0.70 | SLC40A1 (0.57) | SLC40A1L3MBTL1KDM4EMETAP2 | |
| SCHEMBL18434505 | 0.69 | SLC40A1 (0.60) | SLC40A1TSHRMAPTMAPK1 | |
| SCHEMBL18434463 | 0.68 | SLC40A1 (0.67) | SLC40A1KDM4EMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |