Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MITF | O75030 | 2/20 | 0.45 |
| ▸ | ACP1 | P24666 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CASP9 | P55211 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434701 | 0.82 | SLC40A1 (0.67) | SLC40A1KDM4EL3MBTL1MITFPOLB | |
| SCHEMBL18434505 | 0.80 | SLC40A1 (0.60) | SLC40A1MAPTTSHRMAPK1 | |
| SCHEMBL18434714 | 0.80 | SLC40A1 (0.66) | SLC40A1KMT2ALMNASMARCA2KDM4E | |
| SCHEMBL11973775 | 0.78 | SLC40A1 (1.00) | SLC40A1 | |
| SCHEMBL18434820 | 0.78 | SLC40A1 (0.49) | SLC40A1KMT2ALMNAMEN1CASP7 | |
| SCHEMBL18434692 | 0.76 | SLC40A1 (0.67) | SLC40A1KDM4EPARP1HSD17B10 | |
| SCHEMBL18434621 | 0.72 | SLC40A1 (0.65) | SLC40A1 | |
| SCHEMBL18434854 | 0.72 | SLC40A1 (0.59) | SLC40A1KMT2AKDM4EL3MBTL1MITF | |
| SCHEMBL18434688 | 0.71 | SLC40A1 (0.53) | SLC40A1KMT2ALMNAKDM4EL3MBTL1 | |
| SCHEMBL18434660 | 0.71 | SLC40A1 (0.53) | SLC40A1KMT2ALMNAKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |