Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 8/20 | 0.60 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 2/20 | 0.37 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434854 | 0.89 | SLC40A1 (0.59) | SLC40A1METAP1NCF1KCNMA1CCNT1 | |
| SCHEMBL18434621 | 0.81 | SLC40A1 (0.65) | SLC40A1 | |
| SCHEMBL18434820 | 0.81 | SLC40A1 (0.49) | SLC40A1 | |
| SCHEMBL18434712 | 0.80 | SLC40A1 (0.64) | SLC40A1MAPTTSHRMAPK1 | |
| SCHEMBL18434504 | 0.77 | SLC40A1 (0.62) | SLC40A1METAP1NCF1ATRATRIP | |
| SCHEMBL18434688 | 0.76 | SLC40A1 (0.53) | SLC40A1MAPT | |
| SCHEMBL18434660 | 0.76 | SLC40A1 (0.53) | SLC40A1CDK2MAPT | |
| SCHEMBL11972906 | 0.75 | SLC40A1 (1.00) | SLC40A1 | |
| SCHEMBL18434471 | 0.71 | SLC40A1 (0.66) | SLC40A1MAPTTSHR | |
| SCHEMBL18434701 | 0.69 | SLC40A1 (0.67) | SLC40A1MAPTTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |