SCHEMBL184352

SCHEMBL184352

Oc1cccc(-c2ccccn2)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 8/20 0.62
HSD17B2 P37059 8/20 0.62
CYP19A1 P11511 1/20 0.53
RET P07949 1/20 0.52
KDM4E B2RXH2 2/20 0.50
LMNA P02545 2/20 0.50
CCR1 P32246 2/20 0.50
CCR5 P51681 2/20 0.50
CCR8 P51685 2/20 0.50
CYP3A4 P08684 2/20 0.50
CYP2C9 P11712 2/20 0.50
CYP1A2 P05177 1/20 0.50
POLB P06746 1/20 0.50
METAP1 P53582 1/20 0.50
BLM P54132 1/20 0.50
HIF1A Q16665 1/20 0.50
DOHH Q9BU89 1/20 0.50
P4HTM Q9NXG6 1/20 0.50
CYP2A6 P11509 1/20 0.50
KDM1A O60341 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29808134 1.00 HSD17B1 (0.62) HSD17B1HSD17B2CYP19A1RETKDM4E
SCHEMBL29683459 1.00 HSD17B1 (0.62) HSD17B1HSD17B2CYP19A1RETKDM4E
SCHEMBL6831070 0.98 HSD17B1 (0.60) HSD17B1HSD17B2CYP19A1RETKDM4E
Bromide SCHEMBL28022394 0.98 HSD17B1 (0.60) HSD17B1HSD17B2CYP19A1RETKDM4E
SCHEMBL2484955 0.98 HSD17B1 (0.60) HSD17B1HSD17B2CYP19A1RETKDM4E
SCHEMBL647172 0.96 HSD17B1 (0.61) HSD17B1HSD17B2CYP19A1RETKDM4E
SCHEMBL183816 0.94 HSD17B1 (0.56) HSD17B1HSD17B2CYP19A1RETKDM4E
SCHEMBL502867 0.85 KDM4E (0.62) KDM4ELMNACCR1CCR5CCR8
SCHEMBL29679578 0.85 KDM4E (0.62) KDM4ELMNACCR1CCR5CCR8
SCHEMBL6067871 0.83 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0851858-B1 SUBSTITUTED 2-PHENYLPYRIDINES AS HERBICIDES BASF AG (DE) 2002-04-17 EP claimed
US-6010980-A Substituted 2-phenylpyridines as herbicides BASF AKTIENGESELLSCHAFT (DE) 2000-01-04 US claimed
CN-1196722-A Substitued 2-phenylpyridines as herbicides BASF AG (DE) 1998-10-21 CN claimed
EP-0802905-B1 SUBSTITUTED 2-PHENYLPYRIDINES AS HERBICIDES BASF AG (DE) 1998-09-09 EP claimed
EP-0851858-A1 SUBSTITUTED 2-PHENYLPYRIDINES AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-07-08 EP claimed
CN-1183772-A Substituted 2-phenylpyridines BASF AG (DE) 1998-06-03 CN claimed
US-5733850-A HERBICIDES, DESICCANTS OR DEFOLIANTS OF PLANTS BASF AKTIENGESELLSCHAFT (DE) 1998-03-31 US claimed
EP-0802905-A1 SUBSTITUTED 2-PHENYLPYRIDINES AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1997-10-29 EP claimed
WO-1997011059-A1 SUBSTITUTED 2-PHENYLPYRIDINES AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1997-03-27 WO claimed
WO-1996021645-A1 SUBSTITUTED 2-PHENYLPYRIDINES AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1996-07-18 WO claimed
US-20260040755-A1 DIVALENT METAL COMPLEX, PREPARATION METHOD AND USE THEREOF, AND ORGANIC OPTOELECTRONIC DEVICE CHINA PETROLEUM & CHEM CORP (CN) 2026-02-05 US disclosed
EP-4563584-A1 DIVALENT METAL COMPLEX, PREPARATION METHOD THEREFOR AND USE THEREOF, AND ORGANIC OPTOELECTRONIC DEVICE China Petroleum & Chemical Corporation (CN) 2025-06-04 EP disclosed
US-12157748-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-12-03 US disclosed
US-20240360169-A1 BLUE AND NARROW BAND GREEN AND RED EMITTING METAL COMPLEXES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2024-10-31 US disclosed
US-12120945-B2 Display and lighting devices comprising phosphorescent excimers with preferred molecular orientation as monochromatic emitters ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2024-10-15 US disclosed
CN-1196722-A Substitued 2-phenylpyridines as herbicides BASF AG (DE) 1998-10-21 CN disclosed
CN-1183772-A Substituted 2-phenylpyridines BASF AG (DE) 1998-06-03 CN disclosed
US-5747422-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-05-05 US disclosed
US-5733850-A HERBICIDES, DESICCANTS OR DEFOLIANTS OF PLANTS BASF AKTIENGESELLSCHAFT (DE) 1998-03-31 US disclosed
CN-1168135-A Substituted 2-phenylpyridines BASF AG (DE) 1997-12-17 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12157748-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OTC HSD17B1 2801/4885HSD17B2 2528/4885CYP19A1 947/4885
US-20240360169-A1 BLUE AND NARROW BAND GREEN AND RED EMITTING METAL COMPLEXES OCIAD2, OCIAD1, ORC3 HSD17B1 3118/4885HSD17B2 2737/4885CYP19A1 3266/4885
US-20260040755-A1 DIVALENT METAL COMPLEX, PREPARATION METHOD AND USE THEREOF, AND ORGANIC OPTOELECTRONIC DEVICE SCO2, TIMCC, TMCO1 HSD17B1 2548/4885HSD17B2 2263/4885CYP19A1 3159/4885
US-12120945-B2 Display and lighting devices comprising phosphorescent excimers with preferred molecular orientation as monochromatic emitters PDCD1LG2, EML4, EMC3 HSD17B1 4231/4885HSD17B2 3519/4885CYP19A1 4470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.