Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 3/20 | 0.32 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19731980 | 0.87 | ALOX5 (0.43) | ALOX5MAPTALDH1A1RAB9AHPGD | |
| SCHEMBL24161282 | 0.82 | ALOX5 (0.45) | ALOX5MAPTALDH1A1RAB9AHPGD | |
| SCHEMBL15785769 | 0.80 | ALOX5 (0.59) | ALOX5MAPTALDH1A1RAB9AHPGD | |
| SCHEMBL22725239 | 0.80 | MAPT (0.39) | ALOX5MAPTALDH1A1RAB9AHPGD | |
| SCHEMBL6130182 | 0.78 | GPR3 (0.54) | MAPTALDH1A1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL23729369 | 0.76 | GPR3 (0.43) | ALOX5MAPTALDH1A1RAB9AHPGD | |
| SCHEMBL24544697 | 0.76 | MAPT (0.38) | MAPTALDH1A1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL21109946 | 0.76 | MAPT (0.43) | ALOX5MAPTALDH1A1RAB9AHPGD | |
| SCHEMBL15785768 | 0.76 | GPR3 (0.56) | MAPTALDH1A1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL10133864 | 0.76 | BCL2L1 (0.38) | MAPTALDH1A1RAB9AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3124488-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | Universal Display Corporation (US) | 2017-02-01 | — | — | EP | disclosed |