SCHEMBL19731980

SCHEMBL19731980

Cc1ccc2sc3cc(-c4ccc5c(sc6ccccc65)c4C)ccc3c2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.43
MAPT P10636 4/20 0.39
ALDH1A1 P00352 4/20 0.39
RAB9A P51151 2/20 0.39
HPGD P15428 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
L3MBTL1 Q9Y468 3/20 0.37
POLB P06746 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
GPR3 P46089 1/20 0.37
TNKS O95271 1/20 0.36
TNKS2 Q9H2K2 1/20 0.36
KDM4E B2RXH2 2/20 0.34
ATM Q13315 1/20 0.34
LIMK1 P53667 3/20 0.33
DHODH Q02127 1/20 0.33
PRKDC P78527 1/20 0.33
PTPN7 P35236 1/20 0.33
DUSP3 P51452 1/20 0.33
PTPN12 Q05209 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24161282 0.95 ALOX5 (0.45) ALOX5MAPTALDH1A1RAB9AHPGD
SCHEMBL18436200 0.87 ALOX5 (0.41) ALOX5MAPTALDH1A1RAB9AHPGD
SCHEMBL22725239 0.87 MAPT (0.39) ALOX5MAPTALDH1A1RAB9AHPGD
SCHEMBL15785769 0.82 ALOX5 (0.59) ALOX5MAPTALDH1A1RAB9AHPGD
SCHEMBL20858441 0.82 PRKDC (0.41) ALOX5MAPTALDH1A1RAB9AHPGD
SCHEMBL6130182 0.80 GPR3 (0.54) MAPTALDH1A1RAB9AHPGDSMN1; SMN2
SCHEMBL19010414 0.78 GPR3 (0.43) ALOX5MAPTALDH1A1RAB9AHPGD
SCHEMBL21109946 0.78 MAPT (0.43) ALOX5MAPTALDH1A1RAB9AHPGD
SCHEMBL10133864 0.78 BCL2L1 (0.38) MAPTALDH1A1RAB9AHPGDSMN1; SMN2
SCHEMBL15785768 0.78 GPR3 (0.56) MAPTALDH1A1RAB9AHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240244947-A1 ORGANIC LIGHT EMITTING DIODE COMPRISING ORGANOMETALLIC COMPOUND AND PLURALITY OF HOST MATERIALS LG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-11716899-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-01 US disclosed
US-20220348596-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-11-03 US disclosed
US-11208368-B2 Double-spiro type compound and organic light-emitting device containing same LG CHEM, LTD. (KR) 2021-12-28 US disclosed
US-11031560-B2 Compound and organic electronic element comprising same LG CHEM, LTD. (KR) 2021-06-08 US disclosed
US-10968229-B2 Seven-membered ring compounds IDEMITSU KOSAN CO., LTD. (JP) 2021-04-06 US disclosed
US-20200235312-A1 ORGANIC ELECTRONIC MATERIAL AND USE THEREOF HITACHI CHEMICAL COMPANY, LTD. (JP) 2020-07-23 US disclosed
US-20190345082-A1 DOUBLE-SPIRO TYPE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2019-11-14 US disclosed
US-20190119291-A1 SEVEN-MEMBERED RING COMPOUNDS IDEMITSU KOSAN CO., LTD. (JP) 2019-04-25 US disclosed
US-20180138422-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-17 US disclosed
US-20170362241-A1 1-FUNCTIONALIZED DIBENZOFURANS AND DIBENZOTHIOPHENES FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) IDEMITSU KOSAN CO., LTD. (JP) 2017-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220348596-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, AOC2 ALOX5 240/4885MAPT 1575/4885ALDH1A1 75/4885
US-11208368-B2 Double-spiro type compound and organic light-emitting device containing same NR2E3, CRY1, CRY2 ALOX5 3160/4885MAPT 1325/4885ALDH1A1 55/4885
US-11031560-B2 Compound and organic electronic element comprising same OR10J3, ESR1, ETV6 ALOX5 2733/4885MAPT 1791/4885ALDH1A1 1081/4885
US-20190119291-A1 SEVEN-MEMBERED RING COMPOUNDS MCM7, XPO7, LUC7L2 ALOX5 4295/4885MAPT 1506/4885ALDH1A1 2067/4885
US-10968229-B2 Seven-membered ring compounds MCM7, XPO7, LUC7L2 ALOX5 4295/4885MAPT 1506/4885ALDH1A1 2067/4885
US-20190345082-A1 DOUBLE-SPIRO TYPE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING SAME NR2E3, CRY1, CRY2 ALOX5 3160/4885MAPT 1325/4885ALDH1A1 55/4885
US-20240244947-A1 ORGANIC LIGHT EMITTING DIODE COMPRISING ORGANOMETALLIC COMPOUND AND PLURALITY OF HOST MATERIALS PER2, GPX1, SOD1 ALOX5 1310/4885MAPT 899/4885ALDH1A1 13/4885
US-20180138422-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME OR10J3, ESR1, ETV6 ALOX5 2733/4885MAPT 1791/4885ALDH1A1 1081/4885
US-20170362241-A1 1-FUNCTIONALIZED DIBENZOFURANS AND DIBENZOTHIOPHENES FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) OCIAD1, OCIAD2, DDT ALOX5 474/4885MAPT 641/4885ALDH1A1 99/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.