Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3GNRHRMPLPDE3APDE3BPDE4APDE4BPDE4CPDE4DPPARASLC5A2
The experimentally established mechanism targets of Cytarabine 5'-Phosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | GLA | P06280 | 1/20 | 0.75 |
| ▸ | ST6GAL1 | P15907 | 10/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | MTOR | P42345 | 1/20 | 0.60 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.60 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.60 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.57 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.53 |
| ▸ | NT5E | P21589 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Choline SCHEMBL503814 | 0.93 | TSHR (0.81) | TSHRGLAST6GAL1LMNATHRB | |
| Cytarabine 5'-Phosphate SCHEMBL18441374 | 0.92 | TSHR (0.68) | TSHRGLAST6GAL1LMNATHRB | |
| Pyrophosphoric Acid SCHEMBL760216 | 0.91 | TSHR (0.79) | TSHRGLAST6GAL1LMNATHRB | |
| Choline SCHEMBL2446082 | 0.91 | TSHR (0.79) | TSHRGLAST6GAL1LMNATHRB | |
| Cytarabine 5'-Phosphate SCHEMBL859798 | 0.91 | TSHR (0.74) | TSHRGLAST6GAL1LMNATHRB | |
| Cytarabine 5'-Phosphate SCHEMBL2370501 | 0.91 | TSHR (0.74) | TSHRGLAST6GAL1LMNATHRB | |
| Cytarabine 5'-Phosphate SCHEMBL17978431 | 0.90 | TSHR (0.73) | TSHRGLAST6GAL1LMNATHRB | |
| Choline SCHEMBL23199845 | 0.90 | TSHR (0.69) | TSHRGLAST6GAL1LMNATHRB | |
| Choline SCHEMBL28018234 | 0.90 | TSHR (0.76) | TSHRGLAST6GAL1LMNATHRB | |
| Choline SCHEMBL2446073 | 0.89 | TSHR (0.68) | TSHRGLAP2RY2P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017024033-A1 | COMPOSITIONS AND KITS FOR VAPOR PHASE DELIVERY OF ACTIVE COMPOUNDS, METHODS OF MAKING AND USING SAME | ATMOVITA, LLC (US) | 2017-02-09 | — | — | WO | claimed |
| CN-117402198-A | Citicoline salt and preparation method and application thereof | 辽宁科硕营养科技股份有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-114426959-A | Phosphorylcholine cytidine acyl transferase mutant and application thereof | 郑州大学 | 2022-05-03 | — | — | CN | disclosed |
| WO-2017024033-A1 | COMPOSITIONS AND KITS FOR VAPOR PHASE DELIVERY OF ACTIVE COMPOUNDS, METHODS OF MAKING AND USING SAME | ATMOVITA, LLC (US) | 2017-02-09 | — | — | WO | disclosed |