Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Cytarabine 5'-Phosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | GLA | P06280 | 1/20 | 0.73 |
| ▸ | ST6GAL1 | P15907 | 10/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.66 |
| ▸ | MTOR | P42345 | 1/20 | 0.66 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.66 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.66 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.66 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.65 |
| ▸ | NT5E | P21589 | 1/20 | 0.60 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cytarabine 5'-Phosphate SCHEMBL2370501 | 0.99 | TSHR (0.74) | TSHRGLAST6GAL1LMNATHRB | |
| Cytarabine 5'-Phosphate SCHEMBL859798 | 0.99 | TSHR (0.74) | TSHRGLAST6GAL1LMNATHRB | |
| Potassium Ion SCHEMBL10585798 | 0.92 | TSHR (0.80) | TSHRGLAST6GAL1LMNATHRB | |
| SCHEMBL5407898 | 0.91 | TSHR (0.81) | TSHRGLAST6GAL1LMNATHRB | |
| SCHEMBL29356399 | 0.91 | TSHR (0.81) | TSHRGLAST6GAL1LMNATHRB | |
| Cytarabine 5'-Phosphate SCHEMBL18441379 | 0.90 | TSHR (0.75) | TSHRGLAST6GAL1LMNATHRB | |
| Cytarabine 5'-Phosphate SCHEMBL2681941 | 0.89 | P2RY2 (0.69) | TSHRGLAST6GAL1LMNATHRB | |
| SCHEMBL11611645 | 0.89 | P2RY2 (0.75) | TSHRGLAST6GAL1LMNATHRB | |
| Cytarabine 5'-Phosphate SCHEMBL18785109 | 0.89 | P2RY2 (0.69) | TSHRGLAST6GAL1LMNATHRB | |
| Cytarabine 5'-Phosphate SCHEMBL11217191 | 0.89 | P2RY2 (0.69) | TSHRGLAST6GAL1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109607517-A | Partially reduced graphene oxide and preparation method and application thereof | 南京工业大学 | 2019-04-12 | — | — | CN | claimed |
| CN-107114753-A | Common salt substitute, the Foods or drinkses comprising it and application | 日本水产株式会社 | 2017-09-01 | — | — | CN | claimed |
| CN-109607517-A | Partially reduced graphene oxide and preparation method and application thereof | 南京工业大学 | 2019-04-12 | — | — | CN | disclosed |
| CN-109259179-A | Taste improving agent, containing its common salt substitute and for the taste ameliorative way of food | 日本水产株式会社 | 2019-01-25 | — | — | CN | disclosed |
| CN-107114753-A | Common salt substitute, the Foods or drinkses comprising it and application | 日本水产株式会社 | 2017-09-01 | — | — | CN | disclosed |
| WO-2016127262-A1 | MULTIMERIZED ORTHOMYXOVIRUS NUCLEOPROTEIN AND USES THEREOF | FOLIA BIOTECH INC. (CA) | 2016-08-18 | — | — | WO | disclosed |
| CN-103997912-A | Taste improving agent and food or drink containing the same | NIPPON SUISAN KAISHA LTD | 2014-08-20 | — | — | CN | disclosed |