Cytarabine 5'-Phosphate

Cytarabine 5'-Phosphate

SCHEMBL859798

Nc1ccn([C@@H]2O[C@H](COP(=O)([O-])[O-])[C@@H](O)[C@H]2O)c(=O)n1.[Na+].[Na+]

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Cytarabine 5'-Phosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRB known ✓ P10828 1/20 0.67
P2RY2 known ✓ P41231 2/20 0.66
P2RY4 known ✓ P51582 1/20 0.60
TSHR P16473 1/20 0.74
GLA P06280 1/20 0.74
ST6GAL1 P15907 10/20 0.70
LMNA P02545 1/20 0.67
MTOR P42345 1/20 0.67
MDM2 Q00987 1/20 0.67
NCOA1 Q15788 1/20 0.67
NCOA3 Q9Y6Q9 1/20 0.67
NT5E P21589 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cytarabine 5'-Phosphate SCHEMBL2370501 1.00 TSHR (0.74) TSHRGLAST6GAL1LMNATHRB
Cytarabine 5'-Phosphate SCHEMBL17978431 0.99 TSHR (0.73) TSHRGLAST6GAL1LMNATHRB
SCHEMBL29356399 0.92 TSHR (0.81) TSHRGLAST6GAL1LMNATHRB
SCHEMBL5407898 0.92 TSHR (0.81) TSHRGLAST6GAL1LMNATHRB
Cytarabine 5'-Phosphate SCHEMBL18441379 0.91 TSHR (0.75) TSHRGLAST6GAL1LMNATHRB
Potassium Ion SCHEMBL10585798 0.91 TSHR (0.80) TSHRGLAST6GAL1LMNATHRB
Cytarabine 5'-Phosphate SCHEMBL2681941 0.90 P2RY2 (0.69) TSHRGLAST6GAL1LMNATHRB
Cytarabine 5'-Phosphate SCHEMBL18785109 0.90 P2RY2 (0.69) TSHRGLAST6GAL1LMNATHRB
Cytarabine 5'-Phosphate SCHEMBL14669262 0.90 P2RY2 (0.69) TSHRGLAST6GAL1LMNATHRB
SCHEMBL11611645 0.90 P2RY2 (0.75) TSHRGLAST6GAL1LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115820503-B Preparation method of fecal bacteria for intestinal flora transplantation 山东省大健康精准医疗产业技术研究院 2026-05-15 CN claimed
CN-116694525-B Lactobacillus plantarum and application thereof in preparing bacteria agent for inhibiting or relieving or treating oral mucositis 南昌大学 2024-08-06 CN claimed
CN-115595624-B Catalyst for electrocatalytic hydrogenation of cinnamaldehyde and preparation method thereof 天津大学 2024-06-04 CN claimed
CN-116548608-B Full-nutrition formula powder for children and preparation method and application thereof 北安宜品努卡乳业有限公司 2024-01-26 CN claimed
CN-117044789-A Breast milk-imitating balanced 5-dimensional self-stress-resistant nutrition formula milk powder and manufacturing method thereof 至康(杭州)健康科技有限公司 2023-11-14 CN claimed
CN-117016630-A Breast milk protein imitation small molecular structure nutrition formula milk powder and manufacturing method thereof 至康(杭州)健康科技有限公司 2023-11-10 CN claimed
CN-116694525-A Lactobacillus plantarum and application thereof in preparing bacteria agent for inhibiting or relieving or treating oral mucositis 南昌大学 2023-09-05 CN claimed
CN-116548608-A Full-nutrition formula powder for children and preparation method and application thereof 北安宜品努卡乳业有限公司 2023-08-08 CN claimed
CN-116548606-A Nutritional composition suitable for serving as pre-meal load and capable of relieving and increasing sugar and feeling of satiety and application of nutritional composition 中国农业大学 2023-08-08 CN claimed
CN-115820503-A Fecal strain preparation method for intestinal flora transplantation 山东省大健康精准医疗产业技术研究院 2023-03-21 CN claimed
WO-2013012313-A1 USE OF A NUCLEOTIDE FOR IMPROVING THE HEAT STABILITY OF AN AQUEOUS MICELLAR CASEIN COMPOSITION N.V. NUTRICIA (NL) 2013-01-24 WO claimed
WO-2013012324-A1 USE OF A NUCLEOTIDE FOR IMPROVING THE HEAT STABILITY OF AN AQUEOUS MICELLAR CASEIN COMPOSITION N.V. NUTRICIA (NL) 2013-01-24 WO claimed
EP-2544553-A1 CONTROLLING THE TEXTURE OF HIGH-PROTEIN NUTRITIONAL COMPOSITIONS COMPRISING MICELLAR CASEIN N.V. Nutricia (NL) 2013-01-16 EP claimed
CN-102283289-B Anti-inflaming infant formula milk powder and preparation process thereof AUSNUTRIA DAIRY CHINA CO LTD 2012-11-07 CN claimed
CN-102422900-A Formula milk powder for promoting absorption of fatty acid and calcium and preparation method thereof HEILONGJIANG FEIHE DAIRY CO LTD 2012-04-25 CN claimed
CN-102283289-A Anti-inflaming infant formula milk powder and preparation process thereof 2011-12-21 CN claimed
CN-102283288-A Infant formula goat milk powder added with structural grease and preparation method thereof 2011-12-21 CN claimed
WO-2011112075-A1 CONTROLLING THE TEXTURE OF HIGH-PROTEIN NUTRITIONAL COMPOSITIONS COMPRISING MICELLAR CASEIN N.V. NUTRICIA (NL) 2011-09-15 WO claimed
WO-2011112087-A1 CONTROLLING THE TEXTURE OF HIGH-PROTEIN NUTRITIONAL COMPOSITIONS COMPRISING MICELLAR CASEIN N.V. NUTRICIA (NL) 2011-09-15 WO claimed
US-5500668-A INK JET PRINTING XEROX CORPORATION (US) 1996-03-19 US claimed