SCHEMBL184468

SCHEMBL184468

O=[PH](c1cccc2ccccc12)c1cccc2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.46
HSD17B10 Q99714 4/20 0.46
CYP2A6 P11509 3/20 0.46
TSHR P16473 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
CYP1A2 P05177 4/20 0.42
HPGD P15428 2/20 0.42
CYP3A4 P08684 1/20 0.42
KEAP1 Q14145 1/20 0.42
HPRT1 P00492 1/20 0.42
NR4A1 P22736 1/20 0.41
NR4A2 P43354 1/20 0.41
NR4A3 Q92570 1/20 0.41
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 1/20 0.40
PAX8 Q06710 1/20 0.39
HIF1A Q16665 1/20 0.39
CYP1B1 Q16678 1/20 0.39
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29756523 1.00 ALDH1A1 (0.46) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL5440135 0.87 NR4A1 (0.41) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL20593950 0.87 HPRT1 (0.58) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL80143 0.86 CYP1A2 (0.44) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL25798211 0.83 MAPT (0.46) ALDH1A1HSD17B10TDP1HPGDCA1
SCHEMBL21224298 0.81 ALDH1A1 (0.48) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL28143678 0.81 CYP2A6 (0.44) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL27585848 0.80 DEGS1 (0.41) ALDH1A1HSD17B10TDP1CYP1A2HPGD
SCHEMBL27426566 0.78 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL28171688 0.76 MAPT (0.42) ALDH1A1HSD17B10CYP2A6TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1021 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115651017-B Method for selectively preparing benzyl or alkyl phosphine oxide compound based on benzyl thioether derivative 中南大学 2025-05-27 CN claimed
CN-119219696-A Phosphine-containing polycarbonate high-temperature degradation resistant agent, preparation method and polycarbonate composition 万华化学集团股份有限公司 2024-12-31 CN claimed
CN-119101083-A Preparation method and application of cuprous halide-based fluorescent light-emitting material 华东师范大学 2024-12-10 CN claimed
CN-118908997-A Preparation method and application of alpha-phosphonyl imine compound 西华大学 2024-11-08 CN claimed
CN-117417372-A Preparation method of nickel-catalyzed aromatic phosphine oxide compound 中南大学 2024-01-19 CN claimed
CN-117143150-A Preparation method of chiral 2-hydroxyphosphinic oxide and derivative thereof 广西大学 2023-12-01 CN claimed
CN-113214202-B Heterocyclic compound and organic light emitting diode comprising the same 株式会社LG化学 2023-11-21 CN claimed
CN-115651017-A Method for selectively preparing benzyl or alkyl phosphine oxide compound based on benzyl thioether derivative 中南大学 2023-01-31 CN claimed
CN-112010896-B Novel method for preparing phosphonate by oxidative dehydrogenation coupling of copper-catalyzed diaryl phosphorus oxide and alcohol 湖南理工学院 2022-08-19 CN claimed
CN-112010897-B Novel method for preparing thiophosphonate through oxidative dehydrogenation coupling of copper-catalyzed diaryl phosphorus oxide and mercaptan 湖南理工学院 2022-08-19 CN claimed
EP-3351523-B1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEMICAL LTD (KR) 2020-11-04 EP claimed
CN-111574564-A Fluoroalkyl-substituted furyl diphosphine oxygen compound and preparation method thereof 南京工业大学 2020-08-25 CN claimed
CN-111560038-A Fluoroalkyl-substituted furyl monophosphine oxide compound and preparation method thereof 南京工业大学 2020-08-21 CN claimed
US-10651411-B2 Compound and organic light emitting device containing same LG CHEM, LTD. (KR) 2020-05-12 US claimed
US-10421721-B2 Heterocyclic compound and organic light emitting device comprising same LG CHEM, LTD. (KR) 2019-09-24 US claimed
EP-3351531-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LG Chem, Ltd. (KR) 2018-07-25 EP claimed
EP-3351523-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG Chem, Ltd. (KR) 2018-07-25 EP claimed
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2018-05-24 US claimed
US-20180037547-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2018-02-08 US claimed
CN-103885288-A Curable coatings for photoimaging RAINBOW TECHNOLOGY SYSTEMS LTD 2014-06-25 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME CRY1, CRY2, OR10J3 ALDH1A1 87/4885HSD17B10 2296/4885CYP2A6 499/4885
US-10651411-B2 Compound and organic light emitting device containing same CRY1, CRY2, OR10J3 ALDH1A1 87/4885HSD17B10 2296/4885CYP2A6 499/4885
US-10421721-B2 Heterocyclic compound and organic light emitting device comprising same CRY1, CRY2, PER2 ALDH1A1 486/4885HSD17B10 2413/4885CYP2A6 170/4885
US-20180037547-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME CRY1, CRY2, PER2 ALDH1A1 486/4885HSD17B10 2413/4885CYP2A6 170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.