Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | ACP1 | P24666 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1845200 | 0.91 | MEN1 (0.35) | MEN1KMT2AHPGDSMN1; SMN2RAB9A | |
| SCHEMBL12205494 | 0.87 | ACHE (0.38) | MEN1KMT2ATP53HPGDSMN1; SMN2 | |
| SCHEMBL17929227 | 0.85 | KMT2A (0.32) | ACP1MEN1KMT2ATP53L3MBTL1 | |
| SCHEMBL14293568 | 0.82 | EDNRA (0.36) | MEN1KMT2ATP53RAB9AKDM4E | |
| SCHEMBL22145126 | 0.80 | PPARG (0.38) | AHRTP53L3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL5615504 | 0.79 | AHR (0.38) | AHRVDRACP1MEN1KMT2A | |
| SCHEMBL1984131 | 0.79 | EDNRA (0.33) | MEN1KMT2ATP53HPGDSMN1; SMN2 | |
| SCHEMBL25601064 | 0.78 | CYP2C19 (0.33) | AHRACP1MEN1KMT2ATP53 | |
| SCHEMBL6994031 | 0.78 | HSD17B10 (0.35) | RAB9ANPC1 | |
| SCHEMBL25601673 | 0.78 | KIF11 (0.33) | KIF11NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971914-B1 | NEUTRAL COLOURING PHOTOCHROMIC 2H-NAPHTHO 1,2-b PYRANS AND HETEROCYCLIC PYRANS | VIVIMED LABS EUROP LTD (GB) | 2011-05-18 | — | — | EP | disclosed |
| EP-0975619-B1 | INTENSE COLOURING PHOTOCHROMIC 2H-NAPHTHO[1,2-b] PYRANS AND HETEROCYCLIC PYRANS | JAMES ROBINSON LTD (GB) | 2007-01-03 | — | — | EP | disclosed |
| US-6248264-B1 | WINDOWS OR EYEGLASS/SUNGLASS LENSES HAVING GOOD DARKENING AND LIGHTENING PERFORMANCE WITH HIGH OPTICAL DENSITY | JAMES ROBINSON LIMITED (GB) | 2001-06-19 | — | — | US | disclosed |