Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12205494 | 0.96 | ACHE (0.38) | MEN1KMT2ACYP2C19HSD17B10HTT | |
| SCHEMBL17929227 | 0.94 | KMT2A (0.32) | MEN1KMT2ACYP2C19HSD17B10HTT | |
| SCHEMBL14293568 | 0.91 | EDNRA (0.36) | MEN1KMT2ACYP2C19HTTKDM4E | |
| SCHEMBL1844892 | 0.91 | AHR (0.39) | MEN1KMT2AKDM4EHPGDNPC1 | |
| SCHEMBL1984131 | 0.87 | EDNRA (0.33) | MEN1KMT2ACYP2C19HSD17B10HTT | |
| SCHEMBL6994031 | 0.86 | HSD17B10 (0.35) | HSD17B10POLBNPC1RAB9AMAPT | |
| SCHEMBL8978512 | 0.85 | ATM (0.41) | MEN1KMT2ACYP2C19HTTKDM4E | |
| SCHEMBL21452904 | 0.83 | ATM (0.42) | MEN1KMT2ACYP2C19HTTKDM4E | |
| SCHEMBL5751498 | 0.82 | KDM4E (0.42) | MEN1KMT2ACYP2C19HSD17B10HTT | |
| SCHEMBL10102254 | 0.82 | ATM (0.39) | MEN1KMT2ACYP2C19HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118702667-A | Photochromic dye compounds and their use in contact lenses for the correction of the red and green color blindness | 重庆蕾明视光科技有限公司 | 2024-09-27 | — | — | CN | disclosed |
| US-8308995-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2012-11-13 | — | — | US | disclosed |
| US-8308995-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2012-11-13 | — | — | US | disclosed |
| EP-2275418-B1 | CHROMENE COMPOUND | TOKUYAMA CORP (JP) | 2012-10-17 | — | — | EP | disclosed |
| US-20120138876-A1 | CHROMENE COMPOUND | KASAI SOKO (JP) | 2012-06-07 | — | — | US | disclosed |
| US-20120138876-A1 | CHROMENE COMPOUND | KASAI SOKO (JP) | 2012-06-07 | — | — | US | disclosed |
| US-8147726-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2012-04-03 | — | — | US | disclosed |
| US-8147726-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2012-04-03 | — | — | US | disclosed |
| US-20110244244-A1 | COATING COMPOSITION, PROCESS FOR PRODUCING THE COMPOSITION, AND LAMINATE HAVING A HARD COAT LAYER | TOKUYAMA CORPORATION (JP) | 2011-10-06 | — | — | US | disclosed |
| US-20110244244-A1 | COATING COMPOSITION, PROCESS FOR PRODUCING THE COMPOSITION, AND LAMINATE HAVING A HARD COAT LAYER | TOKUYAMA CORPORATION (JP) | 2011-10-06 | — | — | US | disclosed |
| US-6329482-B1 | FOR LENSES | CORNING, S.A. (FR) | 2001-12-11 | — | — | US | disclosed |
| US-6316569-B1 | RESISTANCE TO PHOTO-FATIGUE; FOR OPHTHALMIC APPLICATIONS | CORNING S.A. (FR) | 2001-11-13 | — | — | US | disclosed |
| US-6248264-B1 | WINDOWS OR EYEGLASS/SUNGLASS LENSES HAVING GOOD DARKENING AND LIGHTENING PERFORMANCE WITH HIGH OPTICAL DENSITY | JAMES ROBINSON LIMITED (GB) | 2001-06-19 | — | — | US | disclosed |
| US-6248285-B1 | ACRYLATED ESTER BLENDS | CORNING S.A. (FR) | 2001-06-19 | — | — | US | disclosed |
| EP-0973811-A4 | SELF-LIGHT-STABILIZED PHOTOCHROMIC POLYMER, ITS PREPARATION AND ARTICLES CONTAINING SAME | CORNING SA (FR) | 2000-07-12 | — | — | EP | disclosed |
| EP-0973811-A1 | SELF-LIGHT-STABILIZED PHOTOCHROMIC POLYMER, ITS PREPARATION AND ARTICLES CONTAINING SAME | CORNING INCORPORATED (US) | 2000-01-26 | — | — | EP | disclosed |
| EP-0931278-A4 | PHOTOCHROMIC ORGANIC MATERIAL, ITS MANUFACTURE AND THE PHOTOCHROMIC ARTICLES CONTAINING IT | CORNING INC (US) | 1999-12-29 | — | — | EP | disclosed |
| EP-0931278-A1 | PHOTOCHROMIC ORGANIC MATERIAL, ITS MANUFACTURE AND THE PHOTOCHROMIC ARTICLES CONTAINING IT | CORNING INCORPORATED (US) | 1999-07-28 | — | — | EP | disclosed |
| WO-1998045341-A1 | SELF-LIGHT-STABILIZED PHOTOCHROMIC POLYMER, ITS PREPARATION AND ARTICLES CONTAINING SAME | CORNING INCORPORATED (US) | 1998-10-15 | — | — | WO | disclosed |
| WO-1998016863-A1 | PHOTOCHROMIC ORGANIC MATERIAL, ITS MANUFACTURE AND THE PHOTOCHROMIC ARTICLES CONTAINING IT | CORNING INCORPORATED (US) | 1998-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120138876-A1 | CHROMENE COMPOUND | CHRM1, CBX8, CBX7 | MEN1 270/4885KMT2A 1084/4885CYP2C19 456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.