Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1845200 | 0.86 | MEN1 (0.35) | HSD17B10NPC1POLBMAPTRAB9A | |
| SCHEMBL7971543 | 0.84 | KIF11 (0.40) | HSD17B10NPC1MAPTRAB9A | |
| SCHEMBL12205494 | 0.82 | ACHE (0.38) | HSD17B10NPC1POLBMAPTRAB9A | |
| SCHEMBL9185542 | 0.81 | HSD17B10 (0.33) | HSD17B10NPC1POLBMAPTXBP1 | |
| SCHEMBL7608091 | 0.80 | SMN1; SMN2 (0.41) | NPC1MAPTRAB9A | |
| SCHEMBL12610465 | 0.79 | SMN1; SMN2 (0.34) | NPC1POLBRAB9A | |
| SCHEMBL14293568 | 0.78 | EDNRA (0.36) | NPC1RAB9A | |
| SCHEMBL1844892 | 0.78 | AHR (0.39) | NPC1RAB9A | |
| SCHEMBL7592911 | 0.76 | PARP1 (0.33) | HSD17B10 | |
| SCHEMBL22145138 | 0.74 | KDM4E (0.38) | HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0926146-B1 | CHROMENE COMPOUNDS | TOKUYAMA CORP (JP) | 2003-02-12 | — | — | EP | disclosed |
| US-6197225-B1 | PHOTOCHROMIC LENS MADE OF A POLYMER OF A PHOTOCHROMIC POLYMERIZABLE COMPOSITION | TOKUYAMA CORPORATION (JP) | 2001-03-06 | — | — | US | disclosed |
| EP-0926146-A1 | CHROMENE COMPOUNDS | TOKUYAMA CORPORATION (JP) | 1999-06-30 | — | — | EP | disclosed |