Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18448734 | 0.85 | MAPK1 (0.48) | HIF1ARAB9AAPPAURKAUTS2R | |
| SCHEMBL3953540 | 0.79 | APP (0.53) | MAPTNPC1RAB9AAPPUTS2R | |
| SCHEMBL18448289 | 0.72 | NPC1 (0.55) | NPC1RAB9AMAOAMAOBSMN1; SMN2 | |
| SCHEMBL18449482 | 0.72 | APP (0.53) | MAPTNPC1RAB9AAPPUTS2R | |
| SCHEMBL18449598 | 0.72 | CYP3A4 (0.61) | MAPTNPC1RAB9ALMNAMEN1 | |
| SCHEMBL9579916 | 0.71 | L3MBTL1 (0.70) | MAPTNPC1RAB9AAPPLMNA | |
| SCHEMBL28238899 | 0.70 | FYN (0.51) | HIF1AAPPAURKAMAPK1EGFR | |
| SCHEMBL23202907 | 0.70 | GBA1 (0.41) | MAPTNPC1RAB9AAPPAURKA | |
| SCHEMBL30827843 | 0.70 | GBA1 (0.41) | MAPTNPC1RAB9AAPPAURKA | |
| SCHEMBL18447771 | 0.69 | EGFR (0.47) | AURKAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3331863-A1 | NOVEL COMPOUNDS AS ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2018-06-13 | — | — | EP | disclosed |
| WO-2017021879-A1 | NOVEL COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2017-02-09 | — | — | WO | disclosed |