Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 3/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | LDHB | P07195 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18448734 | 0.84 | MAPK1 (0.48) | EGFRHIF1ABACE1AURKAAPP | |
| SCHEMBL22271053 | 0.73 | HPGD (0.46) | HIF1ACYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL18448955 | 0.70 | HIF1A (0.47) | EGFRHIF1AMAOAAURKAAPP | |
| SCHEMBL8370748 | 0.69 | AURKA (0.52) | EGFRBACE1AURKAAPP | |
| SCHEMBL24137549 | 0.69 | FYN (0.61) | FYNEGFRBACE1MAOAMEN1 | |
| SCHEMBL31631318 | 0.69 | BACE1 (0.65) | EGFRBACE1APPNPSR1MEN1 | |
| SCHEMBL6285864 | 0.69 | BACE1 (0.65) | EGFRBACE1APPNPSR1MEN1 | |
| SCHEMBL5157913 | 0.69 | KDM4E (0.57) | FYNMAOAMEN1KMT2A | |
| SCHEMBL29922555 | 0.69 | KDM4E (0.57) | FYNMAOAMEN1KMT2A | |
| SCHEMBL7459147 | 0.68 | NOS2 (0.66) | FYNEGFRBACE1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368494-A | Methods, compositions and uses of novel FYN kinase inhibitors | 沃伦·C·刘 | 2018-08-03 | — | — | CN | claimed |