SCHEMBL1509166

SCHEMBL1509166

CC(C)(C)OC(=O)N(N)c1ccc(C(=O)ON2C(=O)CCC2=O)cn1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.36
TET2 Q6N021 1/20 0.34
OGFOD1 Q8N543 1/20 0.34
TET1 Q8NFU7 1/20 0.34
EGLN2 Q96KS0 1/20 0.34
EGLN1 Q9GZT9 1/20 0.34
HIF1AN Q9NWT6 1/20 0.34
GPR119 Q8TDV5 2/20 0.33
MAPK1 P28482 1/20 0.32
AAK1 Q2M2I8 1/20 0.32
SIRT2 Q8IXJ6 1/20 0.31
SIRT1 Q96EB6 1/20 0.31
SRD5A1 P18405 1/20 0.31
MT-CO2 P00403 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7910490 0.82 MT-CO2 (0.40) SIRT2SIRT1SRD5A1MT-CO2
SCHEMBL2558802 0.78 HCAR3 (0.48)
SCHEMBL8117544 0.75 POLB (0.37) MT-CO2
SCHEMBL8125489 0.74 LMNA (0.36) MAPK1SRD5A1
SCHEMBL1509167 0.74 GAA (0.41) CRBNTET2OGFOD1TET1EGLN2
SCHEMBL8723112 0.73 KDM4E (0.34) GPR119
SCHEMBL16938414 0.73 GABRP (0.49) CRBNMAPK1
SCHEMBL4758814 0.73 HDAC1 (0.45) MAPK1
SCHEMBL7907251 0.71 NPSR1 (0.35) GPR119MAPK1
SCHEMBL1445644 0.71 MAPK1 (0.40) CRBNMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025105948-A1 [99MTC]TC-IPD-L1 AS A TETRADECAPEPTIDE RADIOPHARMACEUTICAL FOR DETECTING AND MONITORING THE OVEREXPRESSION OF THE PD-L1 PROTEIN INSTITUTO NACIONAL DE INVESTIGACIONES NUCLEARES (MX) 2025-05-22 WO disclosed
CN-107382846-A PSMA bonding agents and application thereof 约翰.霍普金斯大学 2017-11-24 CN disclosed
US-RE46171-E1 Functional biopolymer modification reagents and uses thereof SOLULINK, INCORPORATED (US) 2016-10-04 US disclosed
EP-2298736-B1 Hydrazine-based and carbonyl-based bifunctional crosslinking reagents SOLULINK INC (US) 2015-07-15 EP disclosed
EP-2295407-B1 Hydrazine-based and carbonyl-based bifunctional crosslinking reagents SOLULINK INC (US) 2014-11-05 EP disclosed
EP-1315699-B1 HYDRAZINE-BASED AND CARBONYL-BASED BIFUNCTIONAL CROSSLINKING REAGENTS SOLULINK INC (US) 2013-01-02 EP disclosed
US-7999098-B2 Triphosphate oligonucleotide modification reagents and uses thereof SOLULINK BIOSCIENCES, INC. (US) 2011-08-16 US disclosed
EP-2298736-A1 Hydrazine-based and carbonyl-based bifunctional crosslinking reagents Solulink, Inc. (US) 2011-03-23 EP disclosed
EP-2295407-A1 Hydrazine-based and carbonyl-based bifunctional crosslinking reagents Solulink, Inc. (US) 2011-03-16 EP disclosed
US-7732628-B2 Such as 4-[8-(2-cyanoethyl-N,N-diisopropylphosphoramidyloxy)-2-aza-1-oxooct-1-yl]benzaldehyde, 4-[8-(2-cyanoethyl-N,N-diisopropylphosphoramidyloxy)-2-aza-1-oxooct-1-yl]acetophenone; for incorporation into oligonucleotides during immobilization and conjugation of biopolymers in solid phase synthesis SOLULINK INCORPORATED (US) 2010-06-08 US disclosed
US-5879657-A Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1999-03-09 US disclosed
US-5753520-A BIOCHEMICAL CONJUGATED WITH A HYDRAZINE OR A HYDRAZONE COMPOUND AS DRUG DELIVERY; HIGH BIOLOGICAL SPECIFICITY; MEDICINE FOR IMAGING, THERAPY, RADIOACTIVE TAGGING JOHNSON MATTHEY INC. (US) 1998-05-19 US disclosed
US-5679778-A FOR FORMING CONJUGATES WITH MACROMOLECULES JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1997-10-21 US disclosed
EP-0384769-B1 Protein labelling JOHNSON MATTHEY PLC (GB) 1996-04-24 EP disclosed
EP-0667859-A1 MOLECULE LABELLING USING 2-HYDRANINOPYRIDINE DERIVATIVES JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1995-08-23 EP disclosed
US-5420285-A Imaging for medicine JOHNSON MATTHEY, INC. (US) 1995-05-30 US disclosed
WO-1994022494-A1 RADIOLABELED PLATELET GPIIb/IIIa RECEPTOR ANTAGONISTS AS IMAGING AGENTS FOR THE DIAGNOSIS OF THROMBOEMBOLIC DISORDERS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1994-10-13 WO disclosed
WO-1994010149-A1 MOLECULE LABELLING USING 2-HYDRANINOPYRIDINE DERIVATIVES JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1994-05-11 WO disclosed
US-5206370-A Certain pyridyl hydrazines and hydrazides useful for protein labeling JOHNSON MATTHEY, INC. (US) 1993-04-27 US disclosed
EP-0384769-A2 Protein labelling JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1990-08-29 EP disclosed