SCHEMBL1845396

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1846184	0.89	TAAR1 (0.50)	ADRA2AADRA2CADRA1DADRA1AADRA1B
	SCHEMBL1844126	0.84	ADRA2A (0.55)	ADRA2AADRA2CADRA1DADRA1AADRA1B
	SCHEMBL1844758	0.83	ADRA2A (0.54)	ADRA2AADRA2CADRA1DADRA1AADRA1B
	SCHEMBL1846323	0.81	TAAR1 (0.54)	ADRA2AADRA2CADRA1DADRA1AADRA1B
	SCHEMBL1844588	0.78	GRM4 (0.51)	ADRA2AADRA2CADRA1DADRA1AADRA1B
	SCHEMBL13767327	0.77	ADRA2A (1.00)	ADRA2AADRA2CADRA1DADRA1AADRA1B
	SCHEMBL1845716	0.76	POLB (0.51)	ADRA2AADRA2CADRA1DADRA1AADRA1B
	SCHEMBL1845617	0.76	PTGES (0.46)	ADRA2AADRA2CADRA1DADRA1AADRA1B
	SCHEMBL1847393	0.75	SMN1; SMN2 (0.51)	ADRA2AADRA2CADRA1DADRA1AADRA1B
	Hydrochloric Acid SCHEMBL4058159	0.75	ADRA2A (0.96)	ADRA2AADRA2CADRA1DADRA1AADRA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.