SCHEMBL18456

SCHEMBL18456

O=S(=O)(Cl)c1ccco1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9063607 1.00 CCR2 (0.39)
SCHEMBL6985605 0.93 CCR2 (0.36)
SCHEMBL31506894 0.79 ALDH1A1 (0.39)
SCHEMBL329418 0.77
SCHEMBL2873147 0.75
SCHEMBL1259869 0.75
SCHEMBL353922 0.75
SCHEMBL791265 0.75
SCHEMBL29813636 0.75 CCR2 (0.46)
SCHEMBL11129947 0.73 PSIP1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 407 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116328564-A Method for preparing composite reverse osmosis membrane, composite reverse osmosis membrane prepared by method and application of composite reverse osmosis membrane 沃顿科技股份有限公司 2023-06-27 CN claimed
WO-2023037024-A1 N-SULFONYLUREA DERIVATIVES AND THE THERAPEUTIC USE THEREOF FUNDACION PARA LA INVESTIGACION BIOMEDICA DEL HOSPITAL UNIVERSITARIO DE LA PRINCESA (90%) (ES) 2023-03-16 WO claimed
EP-2046781-A2 SUBSTITUTED FURYL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLINE(THI)ONES Bayer CropScience AG (DE) 2009-04-15 EP claimed
WO-2008006499-A2 SUBSTITUTED FURYL SULFONYLAMINO(THIO)CARBONYL TRIAZOLINE(THI)ONES BAYER CROPSCIENCE AG (DE) 2008-01-17 WO claimed
EP-1021430-A1 FURAN NITRONE COMPOUNDS CENTAUR PHARMACEUTICALS, INC. (US) 2000-07-26 EP claimed
US-6040444-A Process for preparing furan nitrone compounds CENTAUR PHARMACEUTICALS, INC. (US) 2000-03-21 US claimed
WO-1998003496-A1 FURAN NITRONE COMPOUNDS CENTAUR PHARMACEUTICALS, INC. (US) 1998-01-29 WO claimed
US-12612384-B2 Heterocyclic CYP4A inhibitor compounds and compositions thereof MBD Co., Ltd. (KR) 2026-04-28 US disclosed
US-12570647-B2 Amino benzothiazole compounds for treatment of antibiotic resistant bacteria SAINT LOUIS UNIVERSITY (US) 2026-03-10 US disclosed
EP-4684837-A1 NOVEL MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE Temple University of the Commonwealth System of Higher Education (US) 2026-01-28 EP disclosed
US-20250282790-A1 NOVEL MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE PRAEVENTIX, LLC 2025-09-11 US disclosed
EP-3541790-B1 3-(2-(4-PHENYLPIPERAZIN-1-YL)ETHYL)-2-OXA-8-AZASPIRO[4.5]DECAN-1-ONE DERIVATIVES AND RELATED COMPOUNDS AS 5-HYDROXYTRYPTAMINE RECEPTOR 7 (5-HT7) MODULATORS FOR TREATING E.G. INFLAMMATORY BOWEL DISEASE, CIRCADIAN RHYTHM DISORDER OR DEPRESSION UNIV TEMPLE (US) 2025-09-03 EP disclosed
WO-2025136811-A1 CHEMICAL COMPOUNDS AND USES THEREOF IDEAYA BIOSCIENCES, INC. (US) 2025-06-26 WO disclosed
EP-0064804-A2 Thiophene herbicides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-11-17 EP disclosed
EP-0001485-B1 HERBICIDAL SULPHONAMIDES, THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND USE THEREOF E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-05-12 EP disclosed
US-4237130-A DIURETICS, HYPOTENSIVE AGENTS MERCK & CO., INC. (US) 1980-12-02 US disclosed
US-4221585-A N-[(2,6-Dimethoxypyrimidin-4-yl)]aminocarbonyl benzene sulfonamides and their herbicidal compositions and methods of use E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-09-09 US disclosed
US-4169719-A Herbicidal sulfonamides E. I. DU PONT DE NEMOURS AND CO. (US) 1979-10-02 US disclosed
EP-0001485-A2 Herbicidal sulphonamides, their preparation, compositions containing them and use thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 1979-04-18 EP disclosed
US-4115402-A DIURETICS, SALURETICS, URICOSURIC AGENTS MERCK & CO., INC. (US) 1978-09-19 US disclosed