Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18462964 | 0.85 | AR (0.57) | PARP1PARP2MAPTKDM4EPOLB | |
| SCHEMBL20718935 | 0.78 | ABCB1 (0.71) | PARP1PARP2MAPTKDM4EPOLB | |
| SCHEMBL13955211 | 0.76 | TP53 (0.57) | PARP1PARP2MAPTPKMCSNK2A2 | |
| SCHEMBL28009934 | 0.76 | TERT (0.58) | PARP1MAPTKDM4EPOLBGAA | |
| SCHEMBL30269735 | 0.75 | KMT2A (0.68) | PARP1MAPTKDM4EPOLBGAA | |
| SCHEMBL29615754 | 0.75 | KMT2A (0.68) | PARP1MAPTKDM4EPOLBGAA | |
| SCHEMBL10013320 | 0.72 | ABCB1 (0.64) | MAPTKDM4EPOLBGAARECQL | |
| SCHEMBL30956242 | 0.72 | ALDH1A1 (0.70) | MAPTKDM4EPOLBGAARECQL | |
| SCHEMBL3320910 | 0.72 | ALDH1A1 (0.70) | MAPTKDM4EPOLBGAARECQL | |
| SCHEMBL13479744 | 0.71 | CSNK2A2 (0.64) | PARP1PARP2MAPTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9808477-B2 | Use of nobiletin in cancer treatment | MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2017-11-07 | — | — | US | disclosed |
| US-20170143668-A1 | USE OF NOBILETIN IN CANCER TREATMENT | MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2017-05-25 | — | — | US | disclosed |
| US-20170027901-A1 | USE OF NOBILETIN IN CANCER TREATMENT | MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2017-02-02 | — | — | US | disclosed |