Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | BCL2 | P10415 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | CBS | P35520 | 1/20 | 0.55 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.55 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.55 |
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 2/20 | 0.52 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.50 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.49 |
| ▸ | GABRD | O14764 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14066713 | 0.86 | CBS (0.74) | TP53CYP3A4MAPTPTPN1CBS | |
| SCHEMBL13300950 | 0.78 | CYP1B1 (0.77) | TP53CYP3A4MAPTPTPN1CDK5 | |
| SCHEMBL18456430 | 0.76 | PARP1 (0.50) | CYP3A4MAPTPARP1PARP2CSNK2A2 | |
| SCHEMBL14145325 | 0.76 | CYP3A4 (0.76) | TP53CYP3A4MAPTCDK5CDK5R1 | |
| SCHEMBL14144968 | 0.76 | POLH (0.58) | TP53CYP3A4MAPTCDK5CDK5R1 | |
| Hypolaetin SCHEMBL29435843 | 0.75 | BCL2 (0.69) | TP53CYP3A4MAPTBCL2PTPN1 | |
| Hypolaetin SCHEMBL29929136 | 0.75 | BCL2 (0.69) | TP53CYP3A4MAPTBCL2PTPN1 | |
| Hypolaetin SCHEMBL29929121 | 0.75 | BCL2 (0.69) | TP53CYP3A4MAPTBCL2PTPN1 | |
| Hypolaetin SCHEMBL7743466 | 0.75 | BCL2 (0.69) | TP53CYP3A4MAPTBCL2PTPN1 | |
| SCHEMBL28009934 | 0.75 | TERT (0.58) | TP53CYP3A4MAPTBCL2CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009024707-A2 | USE OF RADAMEA MONTANA EXTRACT FOR PREPARING A COSMETIC COMPOSITION | UNIVERSITE CLAUDE BERNARD LYON I (FR) | 2009-02-26 | — | — | WO | disclosed |