Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.54 |
| ▸ | ALPL | P05186 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ALPG | P10696 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18456430 | 0.85 | PARP1 (0.50) | KDM4EINPPL1ALPLPOLBALPI | |
| SCHEMBL30269735 | 0.81 | KMT2A (0.68) | ARKDM4EINPPL1ALPLPOLB | |
| SCHEMBL29615754 | 0.81 | KMT2A (0.68) | ARKDM4EINPPL1ALPLPOLB | |
| SCHEMBL19500382 | 0.78 | AR (0.63) | ARADORA3KDM4EINPPL1ALPL | |
| SCHEMBL10013320 | 0.78 | ABCB1 (0.64) | ARKDM4EINPPL1ALPLPOLB | |
| SCHEMBL28009934 | 0.75 | TERT (0.58) | KDM4EPOLBGAAMAPTRECQL | |
| SCHEMBL16521506 | 0.75 | ADORA3 (0.69) | ARADORA3KDM4EPOLBMAPT | |
| SCHEMBL14066713 | 0.75 | CBS (0.74) | ARKDM4EINPPL1ALPLPOLB | |
| SCHEMBL12636899 | 0.73 | AR (1.00) | ARKDM4EMAPTPKMRECQL | |
| SCHEMBL661087 | 0.72 | ALDH1A1 (0.73) | KDM4EGAAMAPTPKMCCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9808439-B2 | Use of tangeretin in cancer treatment | MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2017-11-07 | — | — | US | disclosed |
| US-20170027900-A1 | USE OF TANGERETIN IN CANCER TREATMENT | MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2017-02-02 | — | — | US | disclosed |