Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.35 |
| ▸ | BTN3A1 | O00481 | 3/20 | 0.35 |
| ▸ | HINT1 | P49773 | 2/20 | 0.35 |
| ▸ | NT5E | P21589 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20402084 | 1.00 | CYP3A4 (0.39) | CYP3A4CYP2C9ADORA3ADORA2AADORA2B | |
| SCHEMBL21136926 | 0.93 | HINT1 (0.42) | CYP3A4CYP2C9ADORA3ADORA2AADORA2B | |
| SCHEMBL20402389 | 0.87 | SERPINA3 (0.41) | CYP3A4CYP2C9ADORA3ADORA2AADORA2B | |
| SCHEMBL20820158 | 0.87 | HINT1 (0.41) | CYP3A4CYP2C9ADORA3ADORA2AADORA2B | |
| SCHEMBL20820132 | 0.87 | HINT1 (0.41) | CYP3A4CYP2C9ADORA3ADORA2AADORA2B | |
| SCHEMBL21136896 | 0.86 | AHCY (0.46) | ADORA3ADORA2B | |
| SCHEMBL21136218 | 0.86 | HINT1 (0.40) | CYP3A4CYP2C9ADORA3ADORA2AADORA2B | |
| SCHEMBL25720930 | 0.84 | CYP3A4 (0.41) | CYP3A4CYP2C9ADORA3ADORA2AADORA2B | |
| SCHEMBL18512911 | 0.84 | CYP3A4 (0.41) | CYP3A4CYP2C9ADORA3ADORA2AADORA2B | |
| SCHEMBL25713585 | 0.84 | CYP3A4 (0.41) | CYP3A4CYP2C9ADORA3ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170029456-A1 | NUCLEOTIDES FOR THE TREATMENT OF LIVER CANCER | IDENIX PHARMACEUTICALS LLC (US) | 2017-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170029456-A1 | NUCLEOTIDES FOR THE TREATMENT OF LIVER CANCER | RNMT, NUDT1, NTPCR | CYP3A4 3731/4885CYP2C9 4137/4885ADORA3 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.