Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 20/20 | 0.71 |
| ▸ | OPRM1 | P35372 | 19/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18458561 | 0.83 | SIGMAR1 (1.00) | SIGMAR1OPRM1KCNH2 | |
| SCHEMBL21337288 | 0.83 | OPRM1 (0.66) | SIGMAR1OPRM1KCNH2 | |
| SCHEMBL21337586 | 0.82 | SIGMAR1 (0.62) | SIGMAR1OPRM1KCNH2 | |
| SCHEMBL20621716 | 0.81 | SIGMAR1 (0.48) | SIGMAR1OPRM1KCNH2 | |
| SCHEMBL18458019 | 0.81 | SIGMAR1 (0.62) | SIGMAR1OPRM1KCNH2 | |
| SCHEMBL21337556 | 0.80 | SIGMAR1 (0.67) | SIGMAR1OPRM1KCNH2 | |
| SCHEMBL21337397 | 0.78 | SIGMAR1 (0.50) | SIGMAR1OPRM1KCNH2 | |
| SCHEMBL20621949 | 0.77 | SIGMAR1 (0.59) | SIGMAR1OPRM1KCNH2 | |
| SCHEMBL18458668 | 0.77 | SIGMAR1 (1.00) | SIGMAR1OPRM1KCNH2 | |
| SCHEMBL21337571 | 0.76 | OPRM1 (0.81) | SIGMAR1OPRM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017016669-A1 | SUBSTITUTED AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2017-02-02 | — | — | WO | disclosed |