Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18458552 | 0.82 | OPRM1 (0.40) | OPRM1SIGMAR1KCNH2 | |
| SCHEMBL18458564 | 0.81 | OPRM1 (0.60) | OPRM1SIGMAR1KCNH2 | |
| SCHEMBL21327063 | 0.76 | OPRM1 (0.36) | OPRM1SIGMAR1KCNH2 | |
| SCHEMBL18458582 | 0.76 | OPRM1 (0.35) | OPRM1SIGMAR1KCNH2 | |
| SCHEMBL18458558 | 0.74 | OPRM1 (0.58) | OPRM1SIGMAR1KCNH2 | |
| SCHEMBL21337259 | 0.74 | OPRM1 (0.39) | OPRM1SIGMAR1KCNH2 | |
| SCHEMBL18458029 | 0.72 | SIGMAR1 (0.55) | OPRM1SIGMAR1KCNH2 | |
| SCHEMBL18458990 | 0.71 | OPRM1 (0.62) | OPRM1SIGMAR1KCNH2 | |
| SCHEMBL18458560 | 0.71 | OPRM1 (0.52) | OPRM1SIGMAR1KCNH2 | |
| SCHEMBL18426749 | 0.71 | OPRM1 (0.37) | OPRM1SIGMAR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017016669-A1 | SUBSTITUTED AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2017-02-02 | — | — | WO | disclosed |