SCHEMBL18458587

SCHEMBL18458587

C=CC1CCC(C2CCC(NCCC)CC2)CC1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.36
DRD3 P35462 1/20 0.36
HTR1A P08908 2/20 0.33
GNAI3 P08754 2/20 0.33
GNAO1 P09471 2/20 0.33
GNAI1 P63096 2/20 0.33
ROCK2 O75116 1/20 0.31
ROCK1 Q13464 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18458588 1.00 DRD2 (0.36) DRD2DRD3HTR1AGNAI3GNAO1
SCHEMBL18559022 0.89 GNAI3 (0.41) DRD2DRD3GNAI3GNAO1GNAI1
SCHEMBL19993065 0.84 GNAI3 (0.41) DRD2DRD3HTR1AGNAI3GNAO1
SCHEMBL18458810 0.80 DRD2 (0.35) DRD2DRD3GNAI3GNAO1GNAI1
SCHEMBL18458589 0.80 DRD2 (0.35) DRD2DRD3GNAI3GNAO1GNAI1
SCHEMBL19204650 0.80 TSHR (0.30) DRD2DRD3HTR1A
SCHEMBL26718738 0.78 GNAI3 (0.37) DRD2DRD3HTR1AGNAI3GNAO1
SCHEMBL18745586 0.77 DRD2 (0.33) DRD2DRD3GNAI3GNAO1GNAI1
SCHEMBL1678882 0.77
SCHEMBL5909386 0.77 GNAI3 (0.45) DRD2DRD3HTR1AGNAI3GNAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230287272-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE DIC CORPORATION (JP) 2023-09-14 US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
US-20230131540-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT AND COMPOUND DIC CORPORATION (JP) 2023-04-27 US disclosed
US-11345857-B2 Spontaneous alignment assistant for liquid crystal compositions DIC CORPORATION (JP) 2022-05-31 US disclosed
US-11326103-B2 Liquid crystal display device DIC CORPORATION (JP) 2022-05-10 US disclosed
US-20220128867-A1 SUBSTRATE AND LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2022-04-28 US disclosed
US-11312906-B2 Polymerizable monomer, liquid crystal composition using polymerizable monomer, and liquid crystal display device DIC CORPORATION (JP) 2022-04-26 US disclosed
US-20210223635-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2021-07-22 US disclosed
US-20210171831-A1 ALIGNMENT AID, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2021-06-10 US disclosed
US-20210139730-A1 DISPERSION AND INKJET INK COMPOSITION, LIGHT CONVERSION LAYER, AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE DISPERSION DIC CORPORATION (JP) 2021-05-13 US disclosed
US-20170253800-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2017-09-07 US disclosed
US-20170226420-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2017-08-10 US disclosed
US-20170218271-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2017-08-03 US disclosed
US-20170210986-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2017-07-27 US disclosed
US-9688913-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-06-27 US disclosed
US-9650572-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-05-16 US disclosed
US-9637684-B2 Composition and liquid crystal display element using same DIC CORPORATION (JP) 2017-05-02 US disclosed
US-9624434-B2 Nematic liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2017-04-18 US disclosed
US-9580654-B2 Liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2017-02-28 US disclosed
US-20170029700-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11345857-B2 Spontaneous alignment assistant for liquid crystal compositions VAC14, VAPA, SFN DRD2 3821/4885DRD3 3702/4885HTR1A 3922/4885
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound OCIAD2, PKN2, SKP1 DRD2 271/4885DRD3 708/4885HTR1A 3667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.