Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 9/20 | 0.40 |
| ▸ | DRD2 | P14416 | 8/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | HTR1B | P28222 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26718738 | 0.93 | GNAI3 (0.37) | GNAI3GNAO1GNAI1DRD3DRD2 | |
| SCHEMBL5909386 | 0.92 | GNAI3 (0.45) | GNAI3GNAO1GNAI1DRD3DRD2 | |
| SCHEMBL1678882 | 0.92 | — | — | |
| SCHEMBL18902153 | 0.91 | ALDH1A1 (0.39) | GNAI3GNAO1GNAI1DRD3DRD2 | |
| Hydrochloric Acid SCHEMBL6818147 | 0.89 | — | — | |
| SCHEMBL21844539 | 0.89 | EPHX1 (0.43) | GNAI3GNAO1GNAI1CYP1A2CYP2D6 | |
| SCHEMBL22945795 | 0.87 | EPHX1 (0.42) | GNAI3GNAO1GNAI1CYP1A2CYP2D6 | |
| SCHEMBL21088923 | 0.84 | GNAI3 (0.41) | GNAI3GNAO1GNAI1DRD3DRD2 | |
| SCHEMBL18458587 | 0.84 | DRD2 (0.36) | GNAI3GNAO1GNAI1DRD3DRD2 | |
| SCHEMBL18458588 | 0.84 | DRD2 (0.36) | GNAI3GNAO1GNAI1DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2883937-B1 | LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME | DAINIPPON INK & CHEMICALS (JP) | 2018-03-21 | — | — | EP | disclosed |