SCHEMBL19085025

SCHEMBL19085025

Cc1ccc2c(c1)-c1ccccc1C2(C)C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 6/20 0.61
ELANE P08246 1/20 0.45
NPSR1 Q6W5P4 2/20 0.45
CASP3 P42574 1/20 0.45
RAB9A P51151 1/20 0.45
ATM Q13315 1/20 0.45
SENP8 Q96LD8 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
PGR P06401 1/20 0.44
HTR2A P28223 2/20 0.43
HTR2C P28335 2/20 0.43
LMNA P02545 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MDM2 Q00987 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ACHE P22303 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19645932 0.89 HTR2A (0.49) PDK2ELANENPSR1CASP3RAB9A
SCHEMBL18463551 0.88 PDK2 (0.56) PDK2ELANENPSR1CASP3RAB9A
SCHEMBL29548566 0.85 PDK2 (0.62) PDK2ELANENPSR1CASP3RAB9A
SCHEMBL6292385 0.85 PDK2 (0.62) PDK2ELANENPSR1CASP3RAB9A
SCHEMBL15281144 0.85 ELANE (0.58) PDK2ELANENPSR1CASP3RAB9A
SCHEMBL5062909 0.82 HTR2A (0.43) PDK2TDP1PGRHTR2AHTR2C
SCHEMBL5014621 0.82 HTR2A (0.43) PDK2TDP1PGRHTR2AHTR2C
SCHEMBL29363404 0.82 HTR2A (0.48) PDK2TDP1L3MBTL1PGRHTR2A
SCHEMBL283246 0.82 HTR2A (0.48) PDK2TDP1L3MBTL1PGRHTR2A
SCHEMBL19885723 0.82 PDK2 (0.64) PDK2ELANENPSR1CASP3RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11839139-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 US disclosed
EP-2602660-B1 Chemically amplified negative resist composition, photo-curable dry film, making method, pattern forming process, and electric/electronic part protecting film SHINETSU CHEMICAL CO (JP) 2019-03-20 EP disclosed
US-20170194573-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170194573-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 PDK2 1304/4885ELANE 2516/4885NPSR1 4463/4885
US-11839139-B2 Organic electroluminescent materials and devices L1CAM, CTCF, RAP1A PDK2 1469/4885ELANE 963/4885NPSR1 1052/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.