Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536164 | 0.89 | DHODH (0.42) | DHODHMALT1MEN1KMT2AALDH1A1 | |
| SCHEMBL10028778 | 0.88 | DHODH (0.41) | DHODHMALT1NTRK1MEN1KMT2A | |
| SCHEMBL28517966 | 0.88 | DHODH (0.41) | DHODHMALT1NTRK1MEN1KMT2A | |
| SCHEMBL782140 | 0.87 | DHODH (0.42) | DHODHMALT1NTRK1KMT2A | |
| SCHEMBL1841264 | 0.86 | DHODH (0.41) | DHODHMALT1TRPV1 | |
| Chlorantraniliprole SCHEMBL29363261 | 0.85 | DHODH (0.44) | DHODHMALT1NTRK1TRPV1 | |
| SCHEMBL30058805 | 0.85 | DHODH (0.44) | DHODHMALT1NTRK1MEN1KMT2A | |
| SCHEMBL678528 | 0.85 | DHODH (0.44) | DHODHMALT1NTRK1LMNAPHGDH | |
| Chlorantraniliprole SCHEMBL29551 | 0.85 | DHODH (0.44) | DHODHMALT1NTRK1TRPV1 | |
| SCHEMBL782370 | 0.85 | DHODH (0.44) | DHODHMALT1NTRK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373210-B1 | HETEROCYCLIC DIAMIDE INVERTEBRATE PEST CONTROL AGENTS | DU PONT (US) | 2011-05-18 | — | — | EP | claimed |
| US-7560564-B2 | Heterocyclic diamide invertebrate pest control agents | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-14 | — | — | US | claimed |
| US-20060205748-A1 | Heterocyclic diamide invertebrate pest control agents | ANNIS GARY D | 2006-09-14 | — | — | US | claimed |
| US-20040102324-A1 | Heterocyclic diamide invertebrate pest control agents | E.I. DU PONT DE NEMOURS AND COMPANY | 2004-05-27 | — | — | US | claimed |
| EP-1373210-A1 | HETEROCYCLIC DIAMIDE INVERTEBRATE PEST CONTROL AGENTS | E. I. du Pont de Nemours and Company (US) | 2004-01-02 | — | — | EP | claimed |
| WO-2002070483-A1 | HETEROCYCLIC DIAMIDE INVERTEBRATE PEST CONTROL AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-09-12 | — | — | WO | claimed |
| EP-1373210-B1 | HETEROCYCLIC DIAMIDE INVERTEBRATE PEST CONTROL AGENTS | DU PONT (US) | 2011-05-18 | — | — | EP | disclosed |
| US-7560564-B2 | Heterocyclic diamide invertebrate pest control agents | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-14 | — | — | US | disclosed |
| US-20060205748-A1 | Heterocyclic diamide invertebrate pest control agents | ANNIS GARY D | 2006-09-14 | — | — | US | disclosed |
| US-20040102324-A1 | Heterocyclic diamide invertebrate pest control agents | E.I. DU PONT DE NEMOURS AND COMPANY | 2004-05-27 | — | — | US | disclosed |
| EP-1373210-A1 | HETEROCYCLIC DIAMIDE INVERTEBRATE PEST CONTROL AGENTS | E. I. du Pont de Nemours and Company (US) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002070483-A1 | HETEROCYCLIC DIAMIDE INVERTEBRATE PEST CONTROL AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205748-A1 | Heterocyclic diamide invertebrate pest control agents | DDT, DBF4, C1S | DHODH 66/4885MALT1 3411/4885NTRK1 2659/4885 |
| US-20040102324-A1 | Heterocyclic diamide invertebrate pest control agents | DDT, DBF4, DDC | DHODH 88/4885MALT1 2307/4885NTRK1 3191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.