SCHEMBL678528

SCHEMBL678528

CNC(=O)c1cc(C)cc(C)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.86

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.44
MALT1 Q9UDY8 2/20 0.36
LMNA P02545 1/20 0.35
GAA P10253 1/20 0.35
GRM4 Q14833 1/20 0.33
POLB P06746 1/20 0.33
RIPK1 Q13546 1/20 0.33
PHGDH O43175 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
LCK P06239 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
NTRK1 P04629 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorantraniliprole SCHEMBL29363261 0.93 DHODH (0.44) DHODHMALT1NTRK1
Chlorantraniliprole SCHEMBL29551 0.93 DHODH (0.44) DHODHMALT1NTRK1
SCHEMBL782370 0.93 DHODH (0.44) DHODHMALT1LMNAGRM4NTRK1
SCHEMBL30058805 0.93 DHODH (0.44) DHODHMALT1LMNAGRM4NTRK1
SCHEMBL24576222 0.92 DHODH (0.44) DHODHMALT1GRM4NTRK1
SCHEMBL10028767 0.91 DHODH (0.45) DHODHMALT1GRM4RIPK1NTRK1
SCHEMBL13287802 0.91 DHODH (0.43) DHODHMALT1GRM4NTRK1
SCHEMBL12528214 0.91 KMT2A (0.38) DHODHMALT1LMNAGAAPHGDH
SCHEMBL31742525 0.90 DHODH (0.43) DHODHMALT1GRM4NTRK1
SCHEMBL14361041 0.90 DHODH (0.43) DHODHMALT1LMNAGAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11812748-B2 Pesticidal combinations UPL LTD (IN) 2023-11-14 US disclosed
US-20150237858-A1 METHOD OF CONTROLLING RYANODINE-MODULATOR INSECTICIDE RESISTANT INSECTS BASF SE (DE) 2015-08-27 US disclosed
US-20150237858-A1 METHOD OF CONTROLLING RYANODINE-MODULATOR INSECTICIDE RESISTANT INSECTS BASF SE (DE) 2015-08-27 US disclosed
US-8841328-B2 Selective insecticides based on anthranilic acid diamides and safeners BAYER CROPSCIENCE AG (DE) 2014-09-23 US disclosed
US-8821898-B2 Active compound combinations having insecticidal and acaricidal properties BAYER CROPSCIENCE AG (DE) 2014-09-02 US disclosed
US-20140087946-A1 Selective Insecticides Based on Anthranilic Acid Diamides and Safeners BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-03-27 US disclosed
EP-2489262-A2 Pesticidal mixtures comprising an anthranilamide insecticide and a fungicide BASF SE (DE) 2012-08-22 EP disclosed
EP-2489264-A2 Pesticidal mixtures comprising an anthranilamide insecticide and a carboxamide fungicide BASF SE (DE) 2012-08-22 EP disclosed
EP-2489268-A2 Pesticidal mixtures comprising an anthranilamide insecticide and a fungicide BASF SE (DE) 2012-08-22 EP disclosed
EP-2489266-A2 Pesticidal mixtures comprising an anthranilamide insecticide and a fungicide BASF SE (DE) 2012-08-22 EP disclosed
EP-2489263-A2 Pesticidal mixtures comprising an anthranilamide insecticide and a fungicide BASF SE (DE) 2012-08-22 EP disclosed
EP-2489267-A2 Pesticidal mixtures comprising an anthranilamide insecticide and a fungicide BASF SE (DE) 2012-08-22 EP disclosed
EP-2489265-A2 Pesticidal mixtures comprising an anthranilamide insecticide and a fungicide BASF SE (DE) 2012-08-22 EP disclosed
US-20110275583-A1 Synergistic active compound combinations BAYER CROPSCIENCE AG (DE) 2011-11-10 US disclosed
US-20110059991-A1 Selective Insecticides Based on Anthranilic Acid Diamides and Safeners BAYER CROPSCIENCE AG (DE) 2011-03-10 US disclosed
US-20100311677-A1 Active Ingredient Combinations Having Insecticidal and Acaricidal Properties BAYER CROPSCIENCE AG (DE) 2010-12-09 US disclosed
US-20090104145-A1 Mixtures of Anthranilamide Invertebrate Pest Control Agents E. I. DU PONT DE NEMOURS AND COMPANY 2009-04-23 US disclosed
WO-2008034785-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO disclosed
WO-2008034787-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO disclosed
US-20070270416-A1 Active Compound Combinations Having Insecticidal and Acaricidal Properties BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-11-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11812748-B2 Pesticidal combinations DDT, BCHE, QDPR DHODH 615/4885MALT1 3217/4885LMNA 4465/4885
US-20140087946-A1 Selective Insecticides Based on Anthranilic Acid Diamides and Safeners DDC, DDT, AADAC DHODH 347/4885MALT1 4492/4885LMNA 1399/4885
US-20090104145-A1 Mixtures of Anthranilamide Invertebrate Pest Control Agents NME4, NLN, STOM DHODH 717/4885MALT1 4217/4885LMNA 4026/4885
US-20110059991-A1 Selective Insecticides Based on Anthranilic Acid Diamides and Safeners DDC, DDT, AADAC DHODH 347/4885MALT1 4492/4885LMNA 1399/4885
US-20070270416-A1 Active Compound Combinations Having Insecticidal and Acaricidal Properties AADAC, ACAA2, AAAS DHODH 2064/4885MALT1 4117/4885LMNA 3039/4885
US-20110275583-A1 Synergistic active compound combinations ACHE, ACAT2, ACAT1 DHODH 1746/4885MALT1 4880/4885LMNA 4235/4885
US-20100311677-A1 Active Ingredient Combinations Having Insecticidal and Acaricidal Properties ACHE, ACAT2, ACAT1 DHODH 899/4885MALT1 4850/4885LMNA 2893/4885
US-20150237858-A1 METHOD OF CONTROLLING RYANODINE-MODULATOR INSECTICIDE RESISTANT INSECTS RYR2, RYR1, CRY1 DHODH 2040/4885MALT1 3778/4885LMNA 3576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.