Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 4/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NCK1 | P16333 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22338535 | 0.94 | CYP2A6 (0.53) | CYP1A2CYP2A6TDP1ESR1ESR2 | |
| SCHEMBL18464129 | 0.84 | CYP2A6 (0.38) | CYP1A2CYP2A6TDP1ESR1ESR2 | |
| SCHEMBL24270298 | 0.81 | GSTP1 (0.52) | CYP1A2ESR1ESR2ALDH1A1CYP2C9 | |
| SCHEMBL862821 | 0.81 | COMT (0.40) | TDP1ALDH1A1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL711834 | 0.79 | GSTP1 (0.57) | CYP1A2CYP2A6CYP3A4CYP2C9CYP11B1 | |
| SCHEMBL20806202 | 0.79 | COMT (0.39) | TDP1ALDH1A1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL24270301 | 0.78 | RAB9A (0.46) | ALDH1A1HPGDTSHRSMN1; SMN2ABL1 | |
| SCHEMBL21537531 | 0.78 | PDE3B (0.34) | CYP1A2CYP2A6ESR1ESR2ALDH1A1 | |
| SCHEMBL20647415 | 0.77 | PDE3B (0.39) | BACE1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL21935453 | 0.75 | PDE3B (0.38) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230053362-A1 | DICHROIC DYE COMPOSITION | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |
| WO-2020158211-A1 | LIQUID CRYSTAL COMPOSITE BODY, LIQUID CRYSTAL LIGHT CONTROL ELEMENT AND LIGHT CONTROL WINDOW | JNC株式会社 | 2020-08-06 | — | — | WO | disclosed |
| US-10723950-B2 | Liquid-crystalline mixtures | MERCK PATENT GMBH (DE) | 2020-07-28 | — | — | US | disclosed |
| EP-3458549-B1 | LIQUID-CRYSTAL MATERIAL | MERCK PATENT GMBH (DE) | 2020-07-22 | — | — | EP | disclosed |
| EP-3400271-B1 | LIQUID-CRYSTALLINE MIXTURES | MERCK PATENT GMBH (DE) | 2020-07-22 | — | — | EP | disclosed |
| EP-3400270-B1 | DEVICE FOR REGULATING ENTRY OF LIGHT | MERCK PATENT GMBH (DE) | 2020-04-29 | — | — | EP | disclosed |
| US-10344217-B2 | Device for controlling the passage of energy, containing a dichroic dye compound | MERCK PATENT GMBH (DE) | 2019-07-09 | — | — | US | disclosed |
| US-10260001-B2 | Liquid crystal material | MERCK PATENT GMBH (DE) | 2019-04-16 | — | — | US | disclosed |
| US-20190016955-A1 | LIQUID-CRYSTALLINE MIXTURES | MERCK PATENT GMBH (DE) | 2019-01-17 | — | — | US | disclosed |
| US-20170029702-A1 | LIQUID CRYSTAL MATERIAL | MERCK PATENT GMBH (DE) | 2017-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10344217-B2 | Device for controlling the passage of energy, containing a dichroic dye compound | CRY1, SLC25A1, CRY2 | CYP1A2 2025/4885CYP2A6 4037/4885TDP1 3077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.