Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22455851 | 0.81 | PTGS1 (0.43) | CA12CA1CA2CA9CA14 | |
| SCHEMBL18857496 | 0.80 | CA12 (0.46) | CA12CA1CA2CA9CA14 | |
| SCHEMBL22455897 | 0.76 | SLC22A12 (0.49) | PTGS1PTGS2 | |
| SCHEMBL10878737 | 0.75 | NR3C1 (0.46) | CA12CA1CA2CA9CA14 | |
| SCHEMBL18854020 | 0.75 | CA12 (0.41) | CA12CA1CA2CA9CA14 | |
| SCHEMBL16884493 | 0.73 | AOC1 (0.56) | KDM4EALDH1A1GLAGAA | |
| SCHEMBL29376653 | 0.73 | AOC1 (0.56) | KDM4EALDH1A1GLAGAA | |
| SCHEMBL18426894 | 0.72 | PTGS1 (0.59) | CA12CA1CA2CA9CA14 | |
| SCHEMBL17737446 | 0.72 | LMNA (0.52) | KDM4EALDH1A1GLAGAA | |
| SCHEMBL18412744 | 0.71 | KMT2A (0.46) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017018924-A1 | RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | MEDIVIR AB (SE) | 2017-02-02 | — | — | WO | disclosed |